RESUGOSBART
UNII 54YJA5WXB9

Substance Identification & Data

This profile provides standardized clinical and technical data for Resugosbart, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 54YJA5WXB9.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2647412-09-5 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

54YJA5WXB9

CAS Registry Number

2647412-09-5

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

RESUGOSBART

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C190336

National Cancer Institute reference terminology for clinical and research data.

INN ID

12244

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Resugosbart. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

RESUGOSBART

Common Names & Synonyms

AB-5 (HUMANIZED MONOCLONAL ANTIBODY TARGETED TO SOLUBLE SCLEROSTIN)

GAMMA4 HEAVY CHAIN (1-444) (VH (HOMO SAPIENS IGHV1-18*01 (79,6%) -(IGHD)-IGHJ4*01 (93,3%), CDR-IMGT (8.8.10) (26-33.51-58.97-106)) (1-117)-HOMO SAPIENS IGHG4*01, IGHG4V5 H P10, NG4M(A) CH2 L92 (CH1 (118-215), HINGE 1-12 S10>P (225) (216-227), CH2 L92 (306) (228-337), CH3 (338-442), CHS (443-444)) (118-444)), (131-214')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-214') ( V-KAPPA (MUS MUSCULUS IGKV6-32*01 (81.9%) -IGKJ1*01 (90,9%)/HOMO SAPIENS IGKV1-39*01 (81.1%) -IGKJ4*01 (91,7%), CDR-IMGT (6.3.9) (27-32.50-52.89-97)) (1'-107')-HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (153),V101 (191) (108'-214')); DIMER (223-223'':226-226'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1SV LACKING THE GLUTAMINE SYNTHETASE (GS-KO) GENE, GLYCOFORM ALFA

IMMUNOGLOBULIN G4 (225-PROLINE), ANTI-(HUMAN SCLEROSTIN) (HUMAN-MUS MUSCULUS MONOCLONAL HR3012221 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL HR3012221 .KAPPA.-CHAIN, DIMER

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS SOST (SCLEROSTIN)), MONOCLONAL ANTIBODY

RESUGOSBART [INN]

SHR-1222 (HUMANIZED MONOCLONAL ANTIBODY TARGETED TO SOLUBLE SCLEROSTIN)