ZIFCASIRAN
UNII 5G6HL9K2G4

Substance Identification & Data

This profile provides standardized clinical and technical data for Zifcasiran, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 5G6HL9K2G4.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2437257-11-7 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

5G6HL9K2G4

CAS Registry Number

2437257-11-7

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

ZIFCASIRAN

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C170918

National Cancer Institute reference terminology for clinical and research data.

INN ID

12163

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

JK-38

Identifier assigned by the United States Adopted Names Council.

Substance Type

Zifcasiran

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Zifcasiran. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

Zifcasiran

Common Names & Synonyms

ARO HIF2 [WHO-DD]

RNA, (CM-SP-AM-AM-CM-GM-UM-AM-AM-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)G-(2'-DEOXY-2'-FLUORO)A-UM-UM-(2'-O-((1-(2-(2-(2-(2-(2-FLUORO-4-((1R)-3-HYDROXY-3-OXO-1-(2-OXO-3-(3-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)PROPYL)-1-IMIDAZOLIDINYL)PROPYL)PHENOXY)ETHOXY)ETHOXY)ETHOXY)ETHYL)-1H-1,2,3-TRIAZOL-4-YL)METHYL))U-CM-(2'-O-((1-(2-(2-(2-(2-(2-FLUORO-4-((1R)-3-HYDROXY-3-OXO-1-(2-OXO-3-(3-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)PROPYL)-1-IMIDAZOLIDINYL)PROPYL)PHENOXY)ETHOXY)ETHOXY)ETHOXY)ETHYL)-1H-1,2,3-TRIAZOL-4-YL)METHYL))A-UM-(2'-O-((1-(2-(2-(2-(2-(2-FLUORO-4-((1R)-3-HYDROXY-3-OXO-1-(2-OXO-3-(3-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)PROPYL)-1-IMIDAZOLIDINYL)PROPYL)PHENOXY)ETHOXY)ETHOXY)ETHOXY)ETHYL)-1H-1,2,3-TRIAZOL-4-YL)METHYL))G-AM-(2'-O-((1-(2-(2-(2-(2-(2-FLUORO-4-((1R)-3-HYDROXY-3-OXO-1-(2-OXO-3-(3-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)PROPYL)-1-IMIDAZOLIDINYL)PROPYL)PHENOXY)ETHOXY)ETHOXY)ETHOXY)ETHYL)-1H-1,2,3-TRIAZOL-4-YL)METHYL))A-AM-(3'->3')-SP-(1'-DE(6-AMINO-9H-PURIN-9-YL))DA), 5'-(O-(25-(1-(2-(2-(2-(2-(2-FLUORO-4-((1R)-3-HYDROXY-3-OXO-1-(2-OXO-3-(3-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)PROPYL)-1-IMIDAZOLIDINYL)PROPYL)PHENOXY)ETHOXY)ETHOXY)ETHOXY)ETHYL)-1H-1,2,3-TRIAZOL-4-YL)-14,14-BIS-(3-((2-(2-((1-(2-(2-(2-(2-(2-FLUORO-4-((1R)-3-HYDROXY-3-OXO-1-(2-OXO-3-(3-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)PROPYL)-1-IMIDAZOLIDINYL)PROPYL)PHENOXY)ETHOXY)ETHOXY)ETHOXY)ETHYL)-1H-1,2,3-TRIAZOL-4-YL)METHOXY)ETHOXY)ETHYL)AMINO)-3-OXOPROPYL)-8,12,17-TRIOXO-21,24-DIOXA-7,13,18-TRIAZAPENTACOS-1-YL) HYDROGEN PHOSPHOROTHIOATE) 5'''-(6-((1-(6-(((2S)-3-HYDROXY-2-((18-HYDROXY-1,18-DIOXOOCTADECYL)AMINO)-3-OXOPROPYL)AMINO)-6-OXOHEXYL)-2,5-DIOXO-3-PYRROLIDINYL)THIO)HEXYL HYDROGEN PHOSPHATE), COMPLEX WITH RNA (UM-SP-(2'-DEOXY-2'-FLUORO)U-SP-UM-SP-(2'-DEOXY-2'-FLUORO)C-AM-(2'-DEOXY-2'-FLUORO)U-GM-(2'-DEOXY-2'-FLUORO)A-AM-(2'-DEOXY-2'-FLUORO)A-UM-(2'-DEOXY-2'-FLUORO)C-GM-(2'-DEOXY-2'-FLUORO)U-UM-(2'-DEOXY-2'-FLUORO)A-CM-(2'-DEOXY-2'-FLUORO)G-UM-(2'-DEOXY-2'-FLUORO)U-SP-GM) (1:1)

ZIFCASIRAN [USAN]

zifcasiran [INN]