ROVOCTOCOGENE DURPARVOVEC
UNII 63QD0BX9B4

Substance Identification & Data

This profile provides standardized clinical and technical data for Rovoctocogene Durparvovec, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 63QD0BX9B4.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2163074-26-6 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
63QD0BX9B4
CAS Registry Number
2163074-26-6
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
ROVOCTOCOGENE DURPARVOVEC
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C175201
National Cancer Institute reference terminology for clinical and research data.
INN ID
10992
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
structurallyDiverse
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Rovoctocogene Durparvovec. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ROVOCTOCOGENE DURPARVOVEC

Common Names & Synonyms

ROVOCTOCOGENE DURPARVOVEC [INN]

Systematic Nomenclature

A RECOMBINANT INTRONLESS NON-REPLICATING ADENO-ASSOCIATED VIRUS 2 VECTOR (AAV2) WITH A BIO-ENGINEERED CAPSID DERIVED BY DNA SHUFFLING OF 10 AAV CAPSID SEQUENCES (AAV1, 2, 3B, 4, 5, 6 8, 9, AVIAN AND BOVINE AAV) FOLLOWED BY IN VIVO SELECTION IN FAH//RAG2//IL2RG/ (FRG) MICE PARTIALLY REPOPULATED WITH HUMAN HEPATOCYTES. THE VECTOR HAS AAV2 GENOMIC INVERTED TERMINAL REPEATS (ITR) AND ENCODES A HUMAN B-DOMAIN-DELETED BLOOD COAGULATION FACTOR VIII (HF8, FACTOR VIII, FVIII) UNDER THE CONTROL OF A MODIFIED TRANSTHYRETIN (TTRM) PROMOTER.

External Clinical & Regulatory Resources

CAS
Common Chemistry
NCATS
Inxight Drugs
NLM
DailyMed Products
NCATS
GSRS Full Record
NIH
NCI Thesaurus