OBECABTAGENE AUTOLEUCEL
UNII 760HJB0YRD

Substance Identification & Data

This profile provides standardized clinical and technical data for Obecabtagene Autoleucel, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 760HJB0YRD.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number N/A and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

760HJB0YRD

CAS Registry Number

N/A

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

OBECABTAGENE AUTOLEUCEL

Official standardized name for this substance within the FDA UNII nomenclature system.

Molecular Formula

760HJB0YRD

The specific atomic composition represented as a molecular structure string.

NCI Thesaurus

C172746

National Cancer Institute reference terminology for clinical and research data.

INN ID

11486

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

JK-262

Identifier assigned by the United States Adopted Names Council.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

ITIS TSN

180092

Taxonomic Serial Number for species identified in the Integrated Taxonomic Information System.

NCBI Taxonomy

9606

Unique numeric identifier used to specify biological species in the NCBI database.

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Obecabtagene Autoleucel. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

OBECABTAGENE AUTOLEUCEL

Common Names & Synonyms

AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) OBTAINED BY APHERESIS TRANSDUCED EX VIVO WITH A NON-REPLICATING, SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING A CHIMERIC ANTIGEN RECEPTOR (CAR) CONSISTING OF AN ANTI-CD19 SPECIFIC SCFV, A CD8.ALPHA. STALK, TRANSMEMBRANE DOMAIN AND ANCHOR, A 41BB ENDODOMAIN AND A CD3 ZETA ENDODOMAIN, UNDER THE CONTROL OF A HUMAN PGK1 PROMOTER AND A MODIFIED WOODCHUCK POST TRANSCRIPTIONAL RESPONSE ELEMENT. THE VECTOR GENOME ALSO CONTAINS A 5' TERMINAL CMV ENHANCER/PROMOTER, A .PSI. PACKAGING SIGNAL, A REV RESPONSE ELEMENT (RRE) AND A CENTRAL POLYPURINE TRACT (CPPT)

OBECABTAGENE AUTOLEUCEL [INN]

OBECABTAGENE AUTOLEUCEL [USAN]

OBECABTAGENE AUTOLEUCEL [WHO-DD]

SELF-INACTIVATING LENTIVIRAL VECTOR CONSISTING OF 5' FUSION BETWEEN THE CMV PROMOTER AND HIV LTR, WHERE THE CMV PROMOTER REPLACES THE U3 REGION. PACKAGING SIGNAL (.PSI.), THE REV RESPONSIVE ELEMENT (RRE) AND THE CENTRAL POLYPURINE TRACT (CPPT) ARE RETAINED. EXPRESSION IS DRIVEN BY THE HUMAN PGK1 PROMOTER, AND EXPRESSION IS ENHANCED BY A MODIFIED WOODCHUCK POST TRANSCRIPTIONAL RESPONSE ELEMENT (MWPRE)