AGERAFENIB
UNII 78I4VEX88N

Substance Identification & Data

This profile provides standardized clinical and technical data for Agerafenib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 78I4VEX88N.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1188910-76-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
78I4VEX88N
CAS Registry Number
1188910-76-0
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
AGERAFENIB
Official standardized name for this substance within the FDA UNII nomenclature system.
InChIKey
C24H22F3N5O5
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
DKNUPRMJNUQNHR-UHFFFAOYSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
10367
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
O(c1c2c(cc(c(c2)OC)OC)ncn1)c3cc(NC(Nc4cc(on4)C(C(F)(F)F)(C)C)=O)ccc3

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Agerafenib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

AGERAFENIB

Common Names & Synonyms

AGERAFENIB [INN]
AGERAFENIB [WHO-DD]
RXDX 105 [WHO-DD]

Systematic Nomenclature

1-(3-((6,7-DIMETHOXYQUINAZOLIN-4-YL)OXY)PHENYL)-3-(5-(1,1,1-TRIFLUORO-2-METHYLPROPAN-2-YL)ISOXAZOL-3-YL)UREA
UREA, N-(3-((6,7-DIMETHOXY-4-QUINAZOLINYL)OXY)PHENYL)-N'-(5-(2,2,2-TRIFLUORO-1,1-DIMETHYLETHYL)-3-ISOXAZOLYL)-

Technical Codes

AB-024
AC-013773
CEP-32496
RXDX-105