UNII 83HN0GTJ6D

CYCLOSPORINE

UNII Information

Unique Ingredient Identifier: 83HN0GTJ6D
The Unique Ingredient Identifier (UNII) is a unique alphanumeric code assigned to a specific substance or ingredient by the FDA (Food and Drug Administration). UNII codes are non-proprietary, free, unique, unambiguous and nonsemantic. Each UNII code consists of 10 characters with both letters and numbers. The first two characters represent the source of the substance while the remaining eight characters represent the specific substance. UNII codes are primarily used to identify and track substances in several drug databases and regulatory documents related to drugs, biologics, and medical devices.
Formula: C62H111N11O12
Molecular Formula, total atoms represented as a molecular structure in a UNII description.
Preferred Substance Name: CYCLOSPORINE
The Preferred Substance Name (PSN) is the official or preferred name of a substance or ingredient. The preferred name provides a standardized and consistent name for each substance is used in the UNII code system. The preferred name may differ from other names also commonly used to refer the same substance. The PSN is usually the name used by regulatory agencies like the FDA.
InChIKey: PMATZTZNYRCHOR-CGLBZJNRSA-N
The InChIKey to a unique identifier for a specific substance or ingredient that is based on its molecular structure. InChIKey stands for International Chemical Identifier Key and is a fixed-length string created from the IUPAC International Chemical Identifier (InChI). The InChIKey is useful in drug development and chemical analysis, where the molecular structure of a substance is an important factor in determining its properties and effects.
SMILES: [C@@]1(N(C([C@@H](N(C([C@@H](N(C([C@@H](N(C([C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)C)=O)C)=O)C)CC(C)C)=O)C)CC(C)C)=O)C)C(C)C)=O)C)([C@@H]([C@@H](C/C=C/C)C)O)[H]
The Simplified Molecular Input Line Entry System or SMILES is a format used to represent and describe the molecular structure of a substance or ingredient. SMILES uses a series of alphanumeric characters to represent the atoms and bonds in a molecule in conjunction with other symbols and operators to indicate the arrangement and connectivity of the atoms.
Registry Number: 59865-13-3
The Registry Number is the unique numerical identifiers assigned to a substance or ingredient by the Chemical Abstracts Service (CAS). The CAS registry number is a used and recognized standard identifier by many industries and regulatory agencies. The Registry Number facilitates cross-referencing substances between different databases that may use different naming conventions or identifiers.
NCI Thesaurus Concept Code: C406
The NCI Thesaurus give reference terminology for many systems. The code includes vocabulary for clinical care, translational research, basic research, public information and administrative activities.
UNII to RxNorm Crosswalk: 3008 (RXCUI)
The RxNorm Ingredient Concept Code is the numeric code assigned to a specific substance or ingredient by the National Library of Medicine's RxNorm system. By including the RxNorm code in the UNII code system it is possible to crossover UNII codes to RxNom.
PubChem Compound ID: 5284373
The PubChem Compound ID is a unique identifier for a specific substance or ingredient in the PubChem database which is the largest collection of freely accessible chemical information by the National Center for Biotechnology Information. The PubChem database is a resource for drug discovery, development, chemical research, and other applications.
INN ID: 5086
Sequential number assigned by World Health Organization's International Nonproprietary Name (INN).
Ingredient Type: INGREDIENT SUBSTANCE
Substance Type: 2017927d-5141-48f8-848d-6c1b26165593
The International Organization for Standardization - ISO 11238 substance type is used as a data element in the UNII code system to provide additional information about the type of substance being identified.

UNII Synonyms and Mappings

The following synonyms and mappings provide alternative ways to refer to the same substance or ingredient. Synonyms may include different names or spellings, alternate chemical names, trade names, or other common names.

  • (R-(R*,R*-(E)))-CYCLIC(L-ALANYL-D-ALANYL-N-METHYL-L-LEUCYL-N-METHYL-L-LEUCYL-N-METHYL-L-VALYL-3-HYDROXY-N,4-DIMETHYL-L-2-AMINO-6-OCTENOYL-L-.ALPHA.-AMINOBUTYRYL-N-METHYLGLYCYL-N-METHYL-L-LEUCYL-L-VALYL-N-METHYL-L-LEUCYL) - Common Name
  • 27-400 - Code
  • ANTIBIOTIC S-7481F1 - Code
  • ATOPICA - Brand/Trade Name
  • CEQUA - Brand/Trade Name
  • CICLOSPORIN - Name identified as having official status
  • CICLOSPORIN [EP MONOGRAPH] - Common Name
  • CICLOSPORIN [INN] - Common Name
  • CICLOSPORIN [JAN] - Common Name
  • CICLOSPORIN [MART.] - Common Name
  • CICLOSPORIN [WHO-DD] - Common Name
  • CICLOSPORIN [WHO-IP] - Common Name
  • CICLOSPORIN A - Common Name
  • CICLOSPORINUM [WHO-IP LATIN] - Common Name
  • CYCLO(((E)-(2S,3R,4R)-3-HYDROXY-4-METHYL-2-(METHYLAMINO)-6-OCTENOYL)-L-2-AMINOBUTYRYL-N-METHYLGLYCYL-N-METHYL-L-LEUCYL-L-VALYL-N-METHYL-L-LEUCYL-L-ALANYL-D-ALANYL-N-METHYL-L-LEUCYL-N-METHYL-L-LEUCYL-N-METHYL-L-VALYL) - Common Name
  • CYCLOSPORIN - Common Name
  • CYCLOSPORIN A - Common Name
  • CYCLOSPORIN A [MI] - Common Name
  • CYCLOSPORINE - Name identified as having official status
  • CYCLOSPORINE [GREEN BOOK] - Common Name
  • CYCLOSPORINE [HSDB] - Common Name
  • CYCLOSPORINE [IARC] - Common Name
  • CYCLOSPORINE [ORANGE BOOK] - Common Name
  • CYCLOSPORINE [USAN] - Common Name
  • CYCLOSPORINE [USP IMPURITY] - Common Name
  • CYCLOSPORINE [USP MONOGRAPH] - Common Name
  • CYCLOSPORINE [USP-RS] - Common Name
  • CYCLOSPORINE [VANDF] - Common Name
  • CYCLOSPORINE A - Common Name
  • CYCLOSPORINE MICROEMULSION - Common Name
  • CYCLOSPORINE, MODIFIED - Common Name
  • EQUORAL - Common Name
  • GENGRAF - Brand/Trade Name
  • IKERVIS - Brand/Trade Name
  • MITOGARD - Brand/Trade Name
  • NEOPLANTA - Common Name
  • NEORAL - Brand/Trade Name
  • NEUROSTAT - Brand/Trade Name
  • NSC-290193 - Code
  • OL-27-400 - Code
  • OPTIMMUNE - Brand/Trade Name
  • RAMIHYPHIN A - Common Name
  • RESTASIS - Brand/Trade Name
  • SANDIMMUN - Brand/Trade Name
  • SANDIMMUNE - Brand/Trade Name
  • SANG-35 - Code
  • SDZ-OXL-400 - Code
  • VERKAZIA - Brand/Trade Name
  • VEVYE - Brand/Trade Name
  • ZINOGRAF ME - Common Name

UNII Resources

Common Chemistry
CAS Common Chemistry is an open community resource of the American Chemical Society for accessing chemical information. The chemical information in the CAS database is curated by expert scientists and includes information of common and frequently regulated chemicals and information applicable to high school and undergraduate chemistry classes.
Inxight Drugs
The National Center for Advancing Translational Sciences (NCATS) Inxight Drugs database has a comprehensive drug development information. The NCATS Inxight Drugs includes manually curated data provided by private companies and FDA. The database has marketing and regulatory status information, rigorous drug ingredient definitions, biological activity, clinical use, etc.
DailyMed Regulated Products
The National Library of Medicine DailyMed is a searchable database that includes the most recent product labeling information submitted to the FDA by private companies.
NCATS GSRS Full Record
The Global Substance Registration System (GSRS) was designed to facilitate global monitoring of human and animal medicinal, food, tobacco, and cosmetic products. GSRS includes unique substance identifiers consistent with the ISO 11238 standard.
NCI Thesaurus
NCI Thesaurus (NCIt) by the National Cancer Institute provides reference terminology for clinical care, translational and basic research, and public information and administrative activities.
PubChem
The PubChem database by the National Library of Medicine includes the chemical structures of small organic molecules and information on their biological activities.

UNII Crossover to NDC Codes

This unique ingredient identifier is listed as an ingredient or substance in the following products in the NDC directory:

NDC Proprietary Name Non-Proprietary Name Dosage Form Route Name Company Name Status
0023-5301Proprietary Name: Restasis Multidose CyclosporineEmulsionOphthalmicAllergan, Inc.ACTIVE
0023-9163Proprietary Name: Restasis CyclosporineEmulsionOphthalmicAllergan, Inc.ACTIVE
0023-9163Proprietary Name: Restasis Allergan, Inc.
0074-0541Proprietary Name: Gengraf Abbvie Inc.
0074-3108Proprietary Name: Gengraf CyclosporineCapsuleOralAbbvie Inc.ACTIVE
0074-3109Proprietary Name: Gengraf CyclosporineCapsuleOralAbbvie Inc.ACTIVE
0074-6463Proprietary Name: Gengraf Abbvie Inc.
0074-6479Proprietary Name: Gengraf Abbvie Inc.
0074-7269Proprietary Name: Gengraf CyclosporineSolutionOralAbbvie Inc.ACTIVE
0078-0109Proprietary Name: Sandimmune CyclosporineInjectionIntravenousNovartis Pharmaceuticals CorporationACTIVE
0078-0110Proprietary Name: Sandimmune CyclosporineSolutionOralNovartis Pharmaceuticals CorporationACTIVE
0078-0240Proprietary Name: Sandimmune CyclosporineCapsule, Liquid FilledOralNovartis Pharmaceuticals CorporationACTIVE
0078-0241Proprietary Name: Sandimmune CyclosporineCapsule, Liquid FilledOralNovartis Pharmaceuticals CorporationACTIVE
0078-0246Proprietary Name: Neoral CyclosporineCapsule, Liquid FilledOralNovartis Pharmaceuticals CorporationACTIVE
0078-0248Proprietary Name: Neoral CyclosporineCapsule, Liquid FilledOralNovartis Pharmaceuticals CorporationACTIVE
0078-0274Proprietary Name: Neoral CyclosporineSolutionOralNovartis Pharmaceuticals CorporationACTIVE
0093-9018Proprietary Name: Cyclosporine ModifiedCyclosporineCapsule, Liquid FilledOralTeva Pharmaceuticals Usa, Inc.ACTIVE
0093-9019Proprietary Name: Cyclosporine ModifiedCyclosporineCapsule, Liquid FilledOralTeva Pharmaceuticals Usa, Inc.ACTIVE
0093-9020Proprietary Name: Cyclosporine ModifiedCyclosporineCapsule, Liquid FilledOralTeva Pharmaceuticals Usa, Inc.ACTIVE
0172-7313Proprietary Name: Cyclosporine CyclosporineSolutionOralTeva Pharmaceuticals Usa, Inc.ACTIVE
0378-8760Proprietary Name: Cyclosporine CyclosporineEmulsionOphthalmicMylan Pharmaceuticals Inc.ACTIVE
0574-0866Proprietary Name: Cyclosporine Padagis Us Llc
10702-808Proprietary Name: Cyclosporine CyclosporineEmulsionOphthalmicKvk-tech, Inc.ACTIVE
23155-837Proprietary Name: Cyclosporine CyclosporineCapsule, Liquid FilledOralHeritage Pharmaceuticals Inc. D/b/a Avet Pharmaceuticals Inc.ACTIVE
23155-838Proprietary Name: Cyclosporine CyclosporineCapsule, Liquid FilledOralHeritage Pharmaceuticals Inc. D/b/a Avet Pharmaceuticals Inc.ACTIVE
23155-839Proprietary Name: Cyclosporine CyclosporineCapsule, Liquid FilledOralHeritage Pharmaceuticals Inc. D/b/a Avet Pharmaceuticals Inc.ACTIVE
47335-506Proprietary Name: Cequa CyclosporineSolution/ DropsOphthalmic; TopicalSun Pharmaceutical Industries, Inc.ACTIVE
47335-507Proprietary Name: Cequa CyclosporineSolution/ DropsOphthalmic; TopicalSun Pharmaceutical Industries, Inc.ACTIVE
50090-1242Proprietary Name: Restasis A-s Medication SolutionsINACTIVATED
50090-4476Proprietary Name: Restasis CyclosporineEmulsionOphthalmicA-s Medication SolutionsACTIVE
51862-458Proprietary Name: Cyclosporine CyclosporineCapsule, Liquid FilledOralMayne Pharma Inc.ACTIVE
51862-460Proprietary Name: Cyclosporine CyclosporineCapsule, Liquid FilledOralMayne Pharma Inc.ACTIVE
54868-4793Proprietary Name: Restasis Physicians Total Care, Inc.INACTIVATED
54868-5522Proprietary Name: Cyclosporine Physicians Total Care, Inc.INACTIVATED
54868-6232Proprietary Name: Cyclosporine Physicians Total Care, Inc.INACTIVATED
60505-0133Proprietary Name: Cyclosporine CyclosporineCapsule, Gelatin CoatedOralApotex Corp.ACTIVE
60505-0134Proprietary Name: Cyclosporine CyclosporineCapsule, Gelatin CoatedOralApotex Corp.ACTIVE
60505-4630Proprietary Name: Cyclosporine, Modfied CyclosporineCapsule, Liquid FilledOralApotex Corp.ACTIVE
60505-4631Proprietary Name: Cyclosporine, Modfied CyclosporineCapsule, Liquid FilledOralApotex Corp.ACTIVE
60505-4632Proprietary Name: Cyclosporine, Modfied CyclosporineCapsule, Liquid FilledOralApotex Corp.ACTIVE
60505-6202Proprietary Name: Cyclosporine CyclosporineEmulsionOphthalmicApotex CorpACTIVE
63629-8640Proprietary Name: Cyclosporine Bryant Ranch Prepack
64380-127Proprietary Name: Cyclosporine CyclosporineCapsule, Liquid FilledOralStrides Pharma Science LimitedACTIVE
64380-128Proprietary Name: Cyclosporine CyclosporineCapsule, Liquid FilledOralStrides Pharma Science LimitedACTIVE
64380-129Proprietary Name: Cyclosporine CyclosporineCapsule, Liquid FilledOralStrides Pharma Science LimitedACTIVE
65086-001Proprietary Name: Verkazia CyclosporineEmulsionOphthalmic; TopicalSanten IncorporatedACTIVE
68084-879Proprietary Name: Cyclosporine CyclosporineCapsule, Gelatin CoatedOralAmerican Health PackagingACTIVE
68084-921Proprietary Name: Cyclosporine CyclosporineCapsule, Gelatin CoatedOralAmerican Health PackagingACTIVE
68180-214Proprietary Name: Cyclosporine CyclosporineEmulsionOphthalmicLupin Pharmaceuticals, Inc.ACTIVE
70261-514Proprietary Name: Cyclosporine/chondroitin Sulfate Pf Imprimisrx NjINACTIVATED
71384-514Proprietary Name: Cyclosporine/chondroitin Pf Imprimis Njof, LlcINACTIVATED
73043-005Proprietary Name: Cyclosporine CyclosporineEmulsionOphthalmicDevatis Inc.ACTIVE
75907-047Proprietary Name: Cyclosporine CyclosporineCapsule, Liquid FilledOralDr. Reddy's Laboratories IncACTIVE
75907-048Proprietary Name: Cyclosporine CyclosporineCapsule, Liquid FilledOralDr. Reddy's Laboratories IncACTIVE
82667-900Proprietary Name: Vevye Cyclosporine Ophthalmic SolutionSolution/ DropsOphthalmicHarrow Eye, LlcACTIVE