AFURESERTIB
UNII 8739X25QI3

Substance Identification & Data

This profile provides standardized clinical and technical data for Afuresertib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 8739X25QI3.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1047644-62-1 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
8739X25QI3
CAS Registry Number
1047644-62-1
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
AFURESERTIB
Official standardized name for this substance within the FDA UNII nomenclature system.
InChIKey
C18H17Cl2FN4OS
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
AFJRDFWMXUECEW-LBPRGKRZSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
9666
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
ZZ-02
Identifier assigned by the United States Adopted Names Council.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
c1(cc(c(s1)Cl)-c2c(cnn2C)Cl)C(=O)N[C@H](CN)Cc3cc(ccc3)F

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Afuresertib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

AFURESERTIB

Common Names & Synonyms

AFURESERTIB [INN]
AFURESERTIB [USAN]
AFURESERTIB [WHO-DD]

Systematic Nomenclature

2-THIOPHENECARBOXAMIDE, N-((1S)-2-AMINO-1-((3-FLUOROPHENYL)METHYL)ETHYL)-5-CHLORO-4-(4-CHLORO-1-METHYL-1H-PYRAZOL-5-YL)-
N-((1S)-1-(AMINOMETHYL)-2-(3-FLUOROPHENYL)ETHYL)-5-CHLORO-4-(4-CHLORO-1-METHYL-1H-PYRAZOL-5-YL)THIOPHENE-2-CARBOXAMIDE
N-((2S)-1-AMINO-3-(3-FLUOROPHENYL)PROPAN-2-YL)-5-CHLORO-4-(4-CHLORO-1-METHYL-1H-PYRAZOL-5-YL)THIOPHENE-2-CARBOXAMIDE

Technical Codes

ASB183
ASB-183
GSK2110183
GSK-2110183
GSK2110183C
GSK-2110183C