IZOKIBEP
UNII 8B8VV1W6FZ

Substance Identification & Data

This profile provides standardized clinical and technical data for Izokibep, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 8B8VV1W6FZ.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2226130-02-3 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

8B8VV1W6FZ

CAS Registry Number

2226130-02-3

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

IZOKIBEP

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C175101

National Cancer Institute reference terminology for clinical and research data.

INN ID

11121

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

JK-250

Identifier assigned by the United States Adopted Names Council.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Izokibep. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

IZOKIBEP

Common Names & Synonyms

ABY-035/AFO2

AFFIBODY ABY-035 (RECOMBINANT HUMAN INTERLEUKIN 17A-BINDING)

FUSION PROTEIN COMPOSED OF 3 BINDING DOMAINS CONSISTING OF THREE-ALPHA-HELIX MOTIFS, EACH DERIVED FROM THE IMMUNOGLOBULIN (IG)-BINDING Z-DOMAIN OF STAPHYLOCOCCAL PROTEIN A (SPA), ENGINEERED FOR BINDING TO TWO HOMODIMER SUBUNITS OF HUMAN INTERLEUKIN 17A (IL17A) WITH THE TWO IDENTICAL N-AND C-TERMINAL DOMAINS (1-58, 116-173) AND TO THE DOMAIN II OF HUMAN SERUM ALBUMIN (HSA) WITH THE CENTRAL DOMAIN (59-110), CONNECTED VIA A G4S PEPTIDE LINKER (111-115); (IL17A-BINDING ENGINEERED SPA PEPTIDE (1-58))-(HSA-BINDING ENGINEERED SPA PEPTIDE (59-110))-(G4S LINKER (111-115))-(IL17ABINDING ENGINEERED SPA PEPTIDE (116-173) FUSION PROTEIN; PRODUCED IN ESCHERICHIA COLI

IZOKIBEP [INN]

IZOKIBEP [USAN]

IZOKIBEP [WHO-DD]