EFBALROPENDEKIN ALFA
UNII 8DQ4YVG4D5

Substance Identification & Data

This profile provides standardized clinical and technical data for Efbalropendekin Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 8DQ4YVG4D5.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2736449-62-8 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
8DQ4YVG4D5
CAS Registry Number
2736449-62-8
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
EFBALROPENDEKIN ALFA
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C199034
National Cancer Institute reference terminology for clinical and research data.
INN ID
12475
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
protein
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Efbalropendekin Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

EFBALROPENDEKIN ALFA

Common Names & Synonyms

EFBALROPENDEKIN ALFA [INN]
HUMAN INTERLEUKIN-15 (IL-15) FRAGMENT (1-114) VARIANT (D30>N, E64>Q, N65>D) FUSED VIA PEPTIDE LINKER 115GGGGS119 TO A HUMAN IMMUNOGLOBULIN G1 C-TERMINAL FC FRAGMENT (120-350) VARIANT, (HOMO SAPIENS IGHG1*03; HINGE: 120-134 (C124S); CH2: 135-243 (E137P, L138V, L139A, G139-140DEL, S170K, Q198E WHEREBY E137P, L138V, L139A, G139-140DEL MATCHES IGHG2*02); CH3: 244-348 (L271D, K273S, N287D, Q321E, N324D, M331L, N337S); CHS: 349-350), DISULFIDE BRIDGE WITH HUMAN INTERLEUKIN-15 RECEPTOR SUBUNIT ALPHA FRAGMENT (1-65) FUSED VIA THE 66GGGGS70 PEPTIDE LINKER TO A HUMAN IMMUNOGLOBULIN G1 FC FRAGMENT (71-301) VARIANT (HOMO SAPIENS IGHG1*03; HINGE: 71-85 C75S); CH2: 86-194 (E88P, L89V, L90A, G90-91DEL, S121K); CH3: 195-299 (E211Q, S218K, M282L, N288S); CHS: 300-301), DISULFIDE BRIDGED HETERODIMER, PRODUCED IN CHINESE HAMSTER OVARY (CHO-M) CELLS, GLYCOFORM ALFA
INTERLEUKIN 15 (30-ASPARAGINE,64-GLUTAMINE,65-ASPARTIC ACID) (HUMAN) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (4-SERINE,18-PROLINE,19-VALINE,20-ALANINE,51-LYSINE,79-GLUTAMIC ACID,140-GLUTAMIC ACID,142-METHIONINE,152-ASPARTIC ACID,154-SERINE,202-GLUTAMIC ACID,205-ASPARTIC ACID,212-LEUCINE,218-SERINE) (HUMAN .GAMMA.1-CHAIN C REGION C-TERMINAL FRAGMENT), (130->81'),(133->84')-BIS(DISULFIDE) 1-65-INTERLEUKIN 15 RECEPTOR SUBUNIT .ALPHA. (HUMAN) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (4-SERINE,18-PROLINE,19-VALINE,20-ALANINE,51-LYSINE,140-GLUTAMIC ACID,141-GLUTAMINE,142-METHIONINE,148-LYSINE,212-LEUCINE,218-SERINE) (HUMAN .GAMMA.1-CHAIN C REGION C-TERMINAL FRAGMENT)

External Clinical & Regulatory Resources

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