ADAGRASIB
UNII 8EOO6HQF8Y

Substance Identification & Data

This profile provides standardized clinical and technical data for Adagrasib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 8EOO6HQF8Y.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2326521-71-3 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

8EOO6HQF8Y

CAS Registry Number

2326521-71-3

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

ADAGRASIB

Official standardized name for this substance within the FDA UNII nomenclature system.

Molecular Formula

8EOO6HQF8Y

The specific atomic composition represented as a molecular structure string.

InChIKey

C32H35ClFN7O2

International Chemical Identifier digital signature for unique molecular identification.

SMILES String

PEMUGDMSUDYLHU-ZEQRLZLVSA-N

Line notation for describing the chemical structure and connectivity of atoms.

NCI Thesaurus

C157493

National Cancer Institute reference terminology for clinical and research data.

PubChem CID

138611145

Unique identification number in the NCBI database of chemical substances.

INN ID

11519

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

KL-25

Identifier assigned by the United States Adopted Names Council.

Substance Type

chemical

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Ingredient Role

C(C[C@@H]1N(CCN(C1)c2c3c(nc(n2)OC[C@@H]4CCCN4C)CN(CC3)c5cccc6cccc(c56)Cl)C(C(=C)F)=O)#N

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Adagrasib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ADAGRASIB

Common Names & Synonyms

ADAGRASIB [INN]

ADAGRASIB [USAN]

ADAGRASIB [WHO-DD]

KRAS G12C INHIBITOR MRTX849

Brand / Trade Names

KRAZATI

Systematic Nomenclature

((2S)-4-(7-(8-CHLORONAPHTHALEN-1-YL)-2-(((2S)-1- METHYLPYRROLIDIN-2-YL)METHOXY)-5,6,7,8- TETRAHYDROPYRIDO(3,4-D)PYRIMIDIN-4-YL)-1-(2-FLUOROPROP2-ENOYL)PIPERAZIN-2-YL)ACETONITRILE

SYS

2-PIPERAZINEACETONITRILE, 4-(7-(8-CHLORO-1-NAPHTHALENYL)-5,6,7,8-TETRAHYDRO-2-(((2S)-1-METHYL-2-PYRROLIDINYL)METHOXY)PYRIDO(3,4-D)PYRIMIDIN-4-YL)-1-(2-FLUORO-1-OXO-2-PROPEN-1-YL)-, (2S)-

SYS