TEGRENMERAN
UNII 8JTY7VW9J8

Substance Identification & Data

This profile provides standardized clinical and technical data for Tegrenmeran, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 8JTY7VW9J8.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2889466-36-6 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

8JTY7VW9J8

CAS Registry Number

2889466-36-6

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

TEGRENMERAN

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C203098

National Cancer Institute reference terminology for clinical and research data.

INN ID

13092

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

nucleicAcid

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Tegrenmeran. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

TEGRENMERAN

Common Names & Synonyms

MESSENGER RNA (MRNA), 5'-CAPPED, ENCODING THE CODON-OPTIMIZED RECEPTOR BINDING DOMAIN (RBD) OF THE SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-COV-2) SPIKE (S) GLYCOPROTEIN (OMICRON SUB-LINEAGES B.1.1.529.4 (BA.4) AND B.1.1.529.5 (BA.5); BASED UPON GISAID: EPI_ISL_12607996), WITH A CYSTEINE TO SERINE SUBSTITUTION AT RESIDUE 233 (CORRESPONDING TO CYS533 IN THE FULL-LENGTH SPIKE GLYCOPROTEIN), EXPRESSED AS A FUSION PROTEIN WITH THE S GLYCOPROTEIN SIGNAL PEPTIDE DERIVED FROM SARS-COV-2 WUHAN-HU 1 STRAIN (GENBANK: MN908947.3), FLANKED BY 5' AND 3' UNTRANSLATED REGIONS (UTRS) DERIVED FROM THE HUMAN .BETA.-GLOBIN GENE AND A 3' POLYADENYLATION (POLYA) TAIL; CONTAINS 5-METHYLURIDINE INSTEAD OF URIDINE (ALL-U>5-ME-U) AND 5-METHYLCYTIDINE INSTEAD OF CYTIDINE (ALL-C>5-ME-C)

RNA (RECOMBINANT 5'-(M7G-(5'->5')-PPP-AM)-CAPPED SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 B.1.1.529.4 AND B.1.1.529.5 VARIANT (1-13)-(319-541)-SPIKE GLYCOPROTEIN PRECURSOR PLUS HUMAN .BETA.-GLOBIN 5'-AND 3'-UNTRANSLATED FLANKING REGION-CONTAINING POLY(A)-TAILED MESSENGER DS16225635), INNER SALT

TEGRENMERAN [INN]

External Clinical & Regulatory Resources

Previous UNII8JTW8HL4PJ

Next UNII8JU4Y2PP36