ENCORAFENIB
UNII 8L7891MRB6

Substance Identification & Data

This profile provides standardized clinical and technical data for Encorafenib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 8L7891MRB6.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1269440-17-6 and the RxNorm Concept ID (RxCUI) 2049106. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
8L7891MRB6
CAS Registry Number
1269440-17-6
RxNorm Concept ID

Detailed Substance Profile

Preferred Name
ENCORAFENIB
Official standardized name for this substance within the FDA UNII nomenclature system.
Molecular Formula
8L7891MRB6
The specific atomic composition represented as a molecular structure string.
InChIKey
C22H27ClFN7O4S
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
CMJCXYNUCSMDBY-ZDUSSCGKSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
9816
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
BC-94
Identifier assigned by the United States Adopted Names Council.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
C(N[C@H](CNc1nc(ccn1)-c2c(nn(c2)C(C)C)-c3c(c(cc(c3)Cl)NS(=O)(=O)C)F)C)(=O)OC

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Encorafenib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ENCORAFENIB

Common Names & Synonyms

CARBAMIC ACID, N-((1S)-2-((4-(3-(5-CHLORO-2-FLUORO-3-((METHYLSULFONYL)AMINO)PHENYL)-1-(1-METHYLETHYL)-1H-PYRAZOL-4-YL)-2-PYRIMIDINYL)AMINO)-1-METHYLETHYL)-, METHYL ESTER
ENCORAFENIB [INN]
ENCORAFENIB [JAN]
ENCORAFENIB [MI]
ENCORAFENIB [ORANGE BOOK]
ENCORAFENIB [USAN]
ENCORAFENIB [WHO-DD]
LGX818
LGX-818

Brand / Trade Names

BRAFTOVI

Systematic Nomenclature

METHYL N-((2S)-1-((4-(3-(5-CHLORO-2-FLUORO-3-(METHANESULFONAMIDO)PHENYL)(-1-(PROPAN-2-YL)-1H-PYRAZOL-4-YL(PYRIMIDIN-2-YL)AMINO)PROPAN-2-YL)CARBAMATE

Technical Codes

NVP-LGX818
NVP-LGX818-NXA
NVP-LGX-818-NXA

NDC Products Containing ENCORAFENIB

This unique ingredient identifier is listed as an ingredient or substance in the following products in the NDC directory: