UNII 8P2N8N28WN

Unique Ingredient Identifier: 8P2N8N28WN

The Unique Ingredient Identifier (UNII) is a unique alphanumeric code assigned to a specific substance or ingredient by the FDA (Food and Drug Administration). UNII codes are non-proprietary, free, unique, unambiguous and nonsemantic. Each UNII code consists of 10 characters with both letters and numbers. The first two characters represent the source of the substance while the remaining eight characters represent the specific substance. UNII codes are primarily used to identify and track substances in several drug databases and regulatory documents related to drugs, biologics, and medical devices.

Preferred Substance Name: EMARETAMIG

The Preferred Substance Name (PSN) is the official or preferred name of a substance or ingredient. The preferred name provides a standardized and consistent name for each substance is used in the UNII code system. The preferred name may differ from other names also commonly used to refer the same substance. The PSN is usually the name used by regulatory agencies like the FDA.

Registry Number: 3051701-97-1

The Registry Number is the unique numerical identifiers assigned to a substance or ingredient by the Chemical Abstracts Service (CAS). The CAS registry number is a used and recognized standard identifier by many industries and regulatory agencies. The Registry Number facilitates cross-referencing substances between different databases that may use different naming conventions or identifiers.

NCI Thesaurus Concept Code: C187658

The NCI Thesaurus give reference terminology for many systems. The code includes vocabulary for clinical care, translational research, basic research, public information and administrative activities.

INN ID: 13773

Sequential number assigned by World Health Organization's International Nonproprietary Name (INN).

Substance Type: protein

The International Organization for Standardization - ISO 11238 substance type is used as a data element in the UNII code system to provide additional information about the type of substance being identified.

The following synonyms and mappings provide alternative ways to refer to the same substance or ingredient. Synonyms may include different names or spellings, alternate chemical names, trade names, or other common names.

• ANTI-CLDN18.2/ANTI-CD3 BISPECIFIC ANTIBODY ASP2138 - Common Name
• ASP 2138 [WHO-DD] - Common Name
• ASP-2138 - Code
• CLAUDIN18.2 X CD3 BISPECIFIC ANTIBODY ASP2138 - Common Name
• EMARETAMIG - Common Name
• EMARETAMIG [INN] - Common Name
• H-GAMMA1 HEAVY CHAIN ANTI-CLDN18 (H) (1-447) (VH (HOMO SAPIENS IGHV5-10-1*01 (89.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT (8.8.11) (26-33.51-58.97-107)) (1-118) -HOMO SAPIENS IGHG1*03V, G1M3>G1M17, NG1M1 CH1 K120, CH3 E12, M14, 1-G1V50 CH2 DELE1.4 P1.3, V1.2, A1.1, 6-G1V51 CH2 K29, 14-G1V72-3 CH1 D114, CH2 E84.2, CH3 D44, E97, D100, 18-G1V82-5 CH3 D24, S26(CH1 N114>D (209), R120>K (215) (119-216), HINGE 1-15 (217-231), CH2 E1.4>DEL, L1.3>P (234), L1.2>V (235), G1.1>A (236), S29>K (267), Q84.2>E (295) (232-340), CH3 E12 (356), M14 (358), L24>D (368), K26>S (370), N44>D (384), Q97>E (418), N100>D (421) (341-445), CHS (446-447)) (119-447)), (221-220')-DISULFIDE WITH L-KAPPA LIGHT CHAIN ANTI-CLDN18 (L') (1'-220') (V-KAPPA (HOMO SAPIENS IGKV4-1*01 (91.1%) -IGKJ2*02 (90.9%) Q120>S (106), CDR-IMGT (12.3.9) (27'-38'.56'-58'.95'-103')) (1'-113') -HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (159'), V101 (197') (114'-220')); G1(VH-CH1-H)-10MER-SCFVLH-10MER-G1(H-CH2-CH3) HEAVY CHAIN ANTI-CLDN18 AND ANTI-CD3E (H'') (1''-720'') (G1(VH-CH1-H) (1''-221'') (VH ANTI-CLDN18 (HOMO SAPIENS IGHV5-10-1*01 (89.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT (8.8.11) (26''-33''.51''-58''.97''-107'')) (1''-118'') -HOMO SAPIENS IGHG1*03V, G1M3>G1M17 CH1 K120 (CH1 R120>K (215'') (119''-216''), HINGE 1-5 (217''-221''))) -10-MER BIS(TETRAGLYCYL-SERYL) LINKER (222''-231'') -SCFVLH ANTI-CD3E (232''-485'') (V-LAMBDA ANTI-CD3E MUSMUS/HOMSAP (MUS MUSCULUS IGLV1*01 (80.6%) -IGLJ1*01 (100%)/HOMO SAPIENS IGLV7-46*01 (76.8%) -IGLJ3*02 (100%), CDR-IMGT (9.3.9) (257''-265''.283''-285''.322''-330'')) (232''-340'') -20-MER TETRAKIS(GLYCYL-LYSYL-PROLYL-GLYCYL-SERYL) LINKER (341''-360'') -VH ANTI-CD3E (HOMO SAPIENS IGHV3-73*01 (88.0%) -(IGHD) -IGHJ6*01 (90.9%) T123>L (480''), CDR-IMGT (8.10.16) (386''-393''.411''-420''.459''-474'')) (361''-485'')) -10-MER BIS(TETRAGLYCYL-SERYL) LINKER (486''-495'') -G1(H-CH2-CH3) (496''-720'') (HOMO SAPIENS IGHG1*03V, NG1M1 CH3 E12, M14, 1-G1V50 CH2 DELE1.4 P1.3, V1.2, A1.1, 6-G1V51 CH2 K29, 18-G1V82-6 CH3 Q13, K20 (HINGE 7-15 (496''-504''), CH2 E1.4>DEL, L1.3>P (507''), L1.2>V (508''), G1.1>A (509''), S29>K (540'') (505''-613''), CH3 E12 (629''), E13>Q (630''), M14 (631''), S20>K (637'') (614''-718''), CHS (719''-720'')))); (221''-220''')-DISULFIDE WITH L-KAPPA LIGHT CHAIN ANTI-CLDN18 (L''')(1'''-220''') (V-KAPPA (HOMO SAPIENS IGKV4-1*01 (91.1%) -IGKJ2*02 (90.9%) Q120>S (106'''), CDR-IMGT (12.3.9) (27'''-38'''.56'''-58'''.95'''-103''')) (1'''-113''') -HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (159'''), V101 (197''') (114'''-220''')); DIMER (227-500'': 230-503'')-BISDISULFIDE, PRODUCED IN A CELL LINE FROM CHINESE HAMSTER OVARY (CHO) CELLS, DERIVED FROM THE CELL LINE CHO-K1, GLYCOFORM ALFA - Common Name
• IMMUNOGLOBULIN (H-GAMMA1_L-KAPPA)_(G1(VH-CH1-H)-10MER-SCFVLH-10MER-G1(H-CH2-CH3)_L-KAPPA), ANTI-(HOMO SAPIENS CLDN18 (CLAUDIN 18, CLAUDIN-18, SURFACTANT ASSOCIATED PROTEIN J, SFTPJ) ISOFORM 2) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), ONOCLONAL ANTIBODY, BISPECIFIC, TRIVALENT (EMARETAMIG) - Common Name
• IMMUNOGLOBULIN G1 (507-PROLINE,508-VALINE,509-ALANINE,DEL-510-GLYCINE,541-LYSINE,631-GLUTAMINE,638-LYSINE), BISPECIFIC, ANTI-(HUMAN CLAUDIN-18.2) (HUMAN-MUS MUSCULUS MONOCLONAL ASP2138 VH-CH1 FRAGMENT) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS)2 FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSILON.-CHAIN) (HUMAN-MUS MUSCULUS MONOCLONAL ASP2138 SINGLE-CHAIN VARIABLE FRAGMENT VL-(GKPGS)4-VH) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS)2 FUSION PROTEIN WITH HUMAN-MUS MUSCULUS MONOCLONAL ASP2138 .GAMMA.1-CHAIN HINGE-CH2-CH3 FRAGMENT, (500->227') (503->230')-BIS(DISULFIDE) WITH IMMUNOGLOBULIN G1 (209'-ASPARTIC ACID,234'-PROLINE,235'-VALINE,236'-ALANINE,DEL-237'-GLYCINE,268'-LYSINE,296'-GLUTAMIC ACID,369'-ASPARTIC ACID,371'-SERINE,385'-ASPARTIC ACID,419'-GLUTAMIC ACID,422'-ASPARTIC ACID) ANTI-(HUMAN CLAUDIN-18.2) (HUMAN-MUS MUSCULUS MONOCLONAL ASP2138 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL ASP2138 .KAPPA.-CHAIN - Common Name

Common Chemistry

CAS Common Chemistry is an open community resource of the American Chemical Society for accessing chemical information. The chemical information in the CAS database is curated by expert scientists and includes information of common and frequently regulated chemicals and information applicable to high school and undergraduate chemistry classes.

Inxight Drugs

The National Center for Advancing Translational Sciences (NCATS) Inxight Drugs database has a comprehensive drug development information. The NCATS Inxight Drugs includes manually curated data provided by private companies and FDA. The database has marketing and regulatory status information, rigorous drug ingredient definitions, biological activity, clinical use, etc.

DailyMed Regulated Products

The National Library of Medicine DailyMed is a searchable database that includes the most recent product labeling information submitted to the FDA by private companies.

NCATS GSRS Full Record

The Global Substance Registration System (GSRS) was designed to facilitate global monitoring of human and animal medicinal, food, tobacco, and cosmetic products. GSRS includes unique substance identifiers consistent with the ISO 11238 standard.

NCI Thesaurus

NCI Thesaurus (NCIt) by the National Cancer Institute provides reference terminology for clinical care, translational and basic research, and public information and administrative activities.