TEZACAFTOR
UNII 8RW88Y506K

Substance Identification & Data

This profile provides standardized clinical and technical data for Tezacaftor, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 8RW88Y506K.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1152311-62-0 and the RxNorm Concept ID (RxCUI) 1999382. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

8RW88Y506K

CAS Registry Number

1152311-62-0

RxNorm Concept ID

1999382

Detailed Substance Profile

Preferred Name

TEZACAFTOR

Official standardized name for this substance within the FDA UNII nomenclature system.

Molecular Formula

8RW88Y506K

The specific atomic composition represented as a molecular structure string.

InChIKey

C26H27F3N2O6

International Chemical Identifier digital signature for unique molecular identification.

SMILES String

MJUVRTYWUMPBTR-MRXNPFEDSA-N

Line notation for describing the chemical structure and connectivity of atoms.

NCI Thesaurus

C152581

National Cancer Institute reference terminology for clinical and research data.

PubChem CID

46199646

Unique identification number in the NCBI database of chemical substances.

INN ID

10104

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

BC-114

Identifier assigned by the United States Adopted Names Council.

Substance Type

chemical

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Ingredient Role

C(Nc1cc2c(cc1F)n(c(c2)C(CO)(C)C)C[C@H](CO)O)(=O)C3(CC3)c4cc5c(cc4)OC(O5)(F)F

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Tezacaftor. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

TEZACAFTOR

Common Names & Synonyms

TEZACAFTOR [INN]

TEZACAFTOR [MI]

TEZACAFTOR [ORANGE BOOK]

TEZACAFTOR [USAN]

TEZACAFTOR [WHO-DD]

Brand / Trade Names

SYMKEVI COMPONENT TEZACAFTOR

TRIKAFTA COMPONENT TEZACAFTOR

Systematic Nomenclature

CYCLOPROPANECARBOXAMIDE, 1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)-N-(1-((2R)-2,3-DIHYDROXYPROPYL)-6-FLUORO-2-(2-HYDROXY-1,1-DIMETHYLETHYL)-1H-INDOL-5-YL)-

SYS