ENCOBERMINOGENE REZMADENOVEC
UNII 93TLW455ZZ

Substance Identification & Data

This profile provides standardized clinical and technical data for Encoberminogene Rezmadenovec, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 93TLW455ZZ.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2376853-01-7 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

93TLW455ZZ

CAS Registry Number

2376853-01-7

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

ENCOBERMINOGENE REZMADENOVEC

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C179083

National Cancer Institute reference terminology for clinical and research data.

INN ID

11543

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

KL-13

Identifier assigned by the United States Adopted Names Council.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Encoberminogene Rezmadenovec. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ENCOBERMINOGENE REZMADENOVEC

Common Names & Synonyms

A REPLICATION-DEFICIENT RECOMBINANT ADENOVIRUS, SEROTYPE 5 (AD5), ENCODING MULTIPLE HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) ISOFORMS (VEGF121, VEGF165 AND VEGF189) UNDER THE CONTROL OF A CYTOMEGALOVIRUS IMMEDIATE EARLY PROMOTER/ENHANCER (CMV) AND THE SIMIAN VIRUS 40 (SV40) POLYA SEQUENCE. ALTERNATIVE SPLICING PROVIDES MRNA THAT ENCODES THE THREE MAJOR ISOFORMS OF VEGF: VEGF121 (EXONS 1-5 AND 8), VEGF165 (EXONS 1-5, 7 AND 8) AND VEGF189 (EXONS 1-5, 6A, 7 AND 8). THE VEGF TRANSGENE IS INSERTED INTO THE REGION FROM WHICH THE ADENOVIRUS EARLY GENE E1A IS DELETED AND E1B IS PARTIALLY DELETED; THE E3 GENE IS DELETED BETWEEN LATE GENE L5 AND THE EARLY GENE E4

A REPLICATION-DEFICIENT RECOMBINANT ADENOVIRUS, SEROTYPE 5, ENCODING MULTIPLE HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) ISOFORMS

DNA (SYNTHETIC HUMAN ADENOVIRUS 5 VECTOR XC001 HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR-SPECIFYING)

ENCOBERMINOGENE REZMADENOVEC [INN]

ENCOBERMINOGENE REZMADENOVEC [USAN]