ILOFOTASE ALFA
UNII 9N4Y2R43OM

Substance Identification & Data

This profile provides standardized clinical and technical data for Ilofotase Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 9N4Y2R43OM.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2387636-92-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

9N4Y2R43OM

CAS Registry Number

2387636-92-0

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

ILOFOTASE ALFA

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C179090

National Cancer Institute reference terminology for clinical and research data.

INN ID

11641

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

JK-253

Identifier assigned by the United States Adopted Names Council.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Ilofotase Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ILOFOTASE ALFA

Common Names & Synonyms

-365-INTESTINAL ALKALINE PHOSPHATASE (279-LEUCINE,328-VALINE) (HUMAN) FUSION PROTEIN WITH 366-430-PLACENTAL ALKALINE PHOSPHATASE (HUMAN) FUSION PROTEIN WITH 431-484-INTESTINAL ALKALINE PHOSPHATASE (478-LEUCINE) (HUMAN), DIMER

CHIMERIC HUMAN ALKALINE PHOSPHATASE (HUMAN INTESTINAL ALKALINE PHOSPHATASE (HIAP) CATALYTIC DOMAIN AND THE HUMAN PLACENTAL ALKALINE PHOSPHATASE (HPLAP) CROWN DOMAIN THAT LACKS THE GLYCOSYLPHOSPHATIDYLINOSITOL (GPI) ANCHOR OF HIAP)

HUMAN INTESTINAL-TYPE ALKALINE PHOSPHATASE (IAP) VARIANT (H279>L, L328>V, P478>L), ENGINEERED BY SUBSTITUTING ITS CROWN DOMAIN (366-430) WITH THE HUMAN PLACENTAL-TYPE ALKALINE PHOSPHATASE (PLACENTAL ALKALINE PHOSPHATASE 1, PLAP-1) CROWN DOMAIN (364-428, 366-430 IN THE CURRENT SEQUENCE), C-TERMINAL LINKED GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR REMOVED, DIMER, GLYCOSYLATED, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS; HUMAN INTESTINAL-TYPE ALKALINE PHOSPHATASE (ALPI, INTESTINAL ALKALINE PHOSPHATASE, IAP) VARIANT (H279>L, L328>V, P478>L) (1-484) WITH ITS CROWN DOMAIN (65-PEPTIDE 366-430) BEING REPLACED BY THE HUMAN PLACENTAL-TYPE ALKALINE PHOSPHATASE (ALPP, ALKALINE PHOSPHATASE REGAN ISOZYME, PLACENTAL ALKALINE PHOSPHATASE 1, PLAP-1) CROWN DOMAIN (65-PEPTIDE 364-428) (366-430), DIMER (481-481')-DISULFIDE, WITHOUT GLYCOSYLPHOSPHATIDYLINOSITOL (GPI) ANCHORS AT ASP-484 AND ASP-484' (SECRETABLE, SOLUBLE ENZYME), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA

HUMAN RECAP

ILOFOTASE ALFA [INN]

ILOFOTASE ALFA [USAN]

RECAP

RECOMBINANT HUMAN ALKALINE PHOSPHATASE (HUMAN INTESTINAL (ALPI), PLACENTAL (ALPP) CHIMERIC PROTEIN)