COMEKIBART
UNII B343W7ZE23

Substance Identification & Data

This profile provides standardized clinical and technical data for Comekibart, uniquely identified by the FDA Unique Ingredient Identifier (UNII) B343W7ZE23.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2833673-47-3 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

B343W7ZE23

CAS Registry Number

2833673-47-3

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

COMEKIBART

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C206895

National Cancer Institute reference terminology for clinical and research data.

INN ID

12879

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Comekibart. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

COMEKIBART

Common Names & Synonyms

COMEKIBART [INN]

IMMUNOGLOBULIN G4, (222-PROLINE,428-LEUCINE,435-SERINE,DE-C-TERMINAL-LYSINE), ANTI-(HUMAN INTERLEUKIN 4 RECEPTOR .ALPHA.) (HUMAN-MUS MUSCULUS MONOCLONAL MG-K10 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MG-K10 .KAPPA.-CHAIN, DIMER

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS IL4R (INTERLEUKIN 4 RECEPTOR, IL4RA, IL-4RA, INTERLEUKIN 13 RECEPTOR, CD124)), HUMANIZED MONOCLONAL ANTIBODY; H-GAMMA4 HEAVY CHAIN HUMANIZED (1-448) (VH (HOMO SAPIENS IGHV3-48*01 (93.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT (8.8.15) (26-33.51-58.97-111)) (1-122) -HOMO SAPIENS IGHG4*01, NG4M(A) CH2 L92, G4V5 H P10, G4V24 CH3 L107, S114 (CH1 (123-220), HINGE 1-12 S10>P (230) (221-232), CH2 L92 (311) (233-342), CH3 M107>L (430), N114>S (436) (343-447), CHS K2>DEL (448)) (123-448)), (136-214')-DISULFIDE WITH L-KAPPA LIGHT CHAIN HUMANIZED (1'-214') (V-KAPPA (HOMO SAPIENS IGKV1-33*01 (89.5%) -IGKJ2*02 (100%), CDR-IMGT (6.3.9) (27'-32'.50'-52'.89'-97')) (1'-107') -HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (153'), V101 (191') (108'-114')); DIMER (228-228'':231-231'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1, GLYCOFORM ALFA