UNII BL5C53FB6H

Unique Ingredient Identifier: BL5C53FB6H

The Unique Ingredient Identifier (UNII) is a unique alphanumeric code assigned to a specific substance or ingredient by the FDA (Food and Drug Administration). UNII codes are non-proprietary, free, unique, unambiguous and nonsemantic. Each UNII code consists of 10 characters with both letters and numbers. The first two characters represent the source of the substance while the remaining eight characters represent the specific substance. UNII codes are primarily used to identify and track substances in several drug databases and regulatory documents related to drugs, biologics, and medical devices.

Preferred Substance Name: TILATAMIG SAMROTECAN

The Preferred Substance Name (PSN) is the official or preferred name of a substance or ingredient. The preferred name provides a standardized and consistent name for each substance is used in the UNII code system. The preferred name may differ from other names also commonly used to refer the same substance. The PSN is usually the name used by regulatory agencies like the FDA.

Registry Number: 2868265-77-2

The Registry Number is the unique numerical identifiers assigned to a substance or ingredient by the Chemical Abstracts Service (CAS). The CAS registry number is a used and recognized standard identifier by many industries and regulatory agencies. The Registry Number facilitates cross-referencing substances between different databases that may use different naming conventions or identifiers.

NCI Thesaurus Concept Code: C192091

The NCI Thesaurus give reference terminology for many systems. The code includes vocabulary for clinical care, translational research, basic research, public information and administrative activities.

INN ID: 13021

Sequential number assigned by World Health Organization's International Nonproprietary Name (INN).

Substance Type: protein

The International Organization for Standardization - ISO 11238 substance type is used as a data element in the UNII code system to provide additional information about the type of substance being identified.

The following synonyms and mappings provide alternative ways to refer to the same substance or ingredient. Synonyms may include different names or spellings, alternate chemical names, trade names, or other common names.

• H-GAMMA1 HEAVY CHAIN ANTI-MET HOMO SAPIENS (1-446) (VH (HOMO SAPIENS IGHV1-8*01 (95.9%) -(IGHD) -IGHJ3*01 (100%), CDR-IMGT (8.8.9) (26-33.51-58.97-105)) (1-116)-HOMO SAPIENS IGHG1*03, G1M3, NG1M1 CH1 R120, CH3 E12, M14, G1V39 CH2 F1.3, E1.2, S116, G1V33 CH3 S22, A24, V86 (HOLE), G1V75 CH3 C5 (CH1 R120 (213) (117-214), HINGE 1-15 (215-229), CH2 L1.3>F (233), L1.2>E (234), P116>S (330) (230-339), CH3 Y5>C (348), E12 (355), M14 (357) T22>S (365), L24>A (367), Y86>V (406) (HOLE) (340-444), CHS (445-446)) (117-446)), (219-214')-DISULFIDE WITH L-KAPPA LIGHT CHAIN ANTI-MET HOMO SAPIENS (1'-214') (V-KAPPA (HOMO SAPIENS IGKV1-5*03 (92.6%) -IGKJ4*01 (90.9%) V124>L (104'), CDRIMGT (6.3.9) (27'-32'.50'-52'.89'-97')) (1'-107') -HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (153'), V101 (191') (108'-214')); H-GAMMA1 HEAVY CHAIN ANTI-EGFR HOMO SAPIENS (1''-454'') (VH (HOMO SAPIENS IGHV1-69*06 (83.7%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT (8.8.17) (26''-33''.51''-58''.97''-113'')) (1''-124'') -HOMO SAPIENS IGHG1*03, G1M3, NG1M1 CH1 R120, CH3 E12, M14, G1V39 CH2 F1.3, E1.2, S116, G1V32 CH3 W22 (KNOB), G1V74 CH3 C10, G1V58 CH1 C5, H V5 (CH1 F5>C (133''), R120 (221'') (125''-222''), HINGE 1-15 C5>V (227'') (223''-237''), CH2 L1.3>F (241''), L1.2>E (242''), P116>S (338'') (238''-347''), CH3 S10>C (361''), E12 (363''), M14 (365''), T22>W (373'') (348''-452''), CHS (453''-454'')) (125''-454'')), (133''-126''')-DISULFIDE WITH L-LAMBDA2 LIGHT CHAIN ANTI-EGFR HOMO SAPIENS (1'''-217''') (V-LAMBDA (HOMO SAPIENS IGLV2-14*05 (94.9%) -IGLJ2*01 (90.9%), CDR-IMGT (9.3.11) (26'''-34'''.52'''-54'''.91'''-101''')) (1'''-111''') -HOMO SAPIENS IGLC2*01 (98.1%), LC2V58 C10, V126, S10>C (126'''), C126>V (216''') (112'''-217''')); DIMER (225-233'':228-236'')-BISDISULFIDE, PRODUCED IN A CELL LINE FROM CHINESE HAMSTER OVARY (CHO) CELLS, DERIVED FROM THE CELL LINE CHO-K1, GLYCOFORM ALFA; SUBSTITUTED AT THE SULFUR ATOMS OF L-CYSTEINYL RESIDUES 233, 236, 219'', 225'', 228'' AND 214''' WITH RADICAL GROUP 1-((2S,5S)-1-(((9S)-9-ETHYL-9-HYDROXY-10,13-DIOXO-2,3,9,10,13,15-HEXAHYDRO-1H,12HBENZO( DE)PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLIN-4-YL)AMINO)-2-METHYL-1,4,7,35-TETRAOXO-5-(PROPAN-2-YL)-10,13,16,19,22,25,28,31-OCTAOXA-3,6,34-TRIAZAHEPTATRIACONTAN-37-YL)-2,5-DIOXOPYRROLIDIN-3-YL (SAMROTECAN) - Common Name
• IMMUNOGLOBULIN G1 (133-CYSTEINE,227-VALINE,241-PHENYLALANINE,242-GLUTAMIC ACID,338-SERINE, 361-CYSTEINE,373-TRYPTOPHAN), ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR) (HUMAN MONOCLONAL RAA22 .GAMMA.1-CHAIN), (133->126'')-DISULFIDE WITH (126-CYSTEINE,216-VALINE) HUMAN MONOCLONAL RAA22 .LAMBDA.-CHAIN, (361->348')-DISULFIDE WITH IMMUNOGLOBULIN G1 (233-PHENYLALANINE,234-GLUTAMIC ACID,330-SERINE,348-CYSTEINE,365-SERINE,367-ALANINE,406-VALINE) ANTI-(HUMAN HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET) (HUMAN MONOCLONAL B09 .GAMMA.1-CHAIN) COMPLEX WITH HUMAN MONOCLONAL B09 .KAPPA.-CHAIN, 214'',219,225,228,233',236'-HEXAKIS(THIOETHER) WITH N-(31-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1,29-DIOXO-4,7,10,13,16,19,22,25-OCTAOXA-28-AZAHENTRIACONT-1-YL)-L-VALYL-N-((9S)-9-ETHYL-2,3,9,10,13,15-HEXAHYDRO-9-HYDROXY-10,13-DIOXO-1H,12H-BENZO(DE)PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLIN-4-YL)-L-ALANINAMIDE - Common Name
• IMMUNOGLOBULIN G1-KAPPA/G1-LAMBDA, ANTI-(HOMO SAPIENS MET (MET PROTO-ONCOGENE, HEPATOCYTE GROWTH FACTOR (HGF) RECEPTOR, HGFR, SCATTER FACTOR (SF) RECEPTOR, HGF/SF RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE C-MET, PAPILLARY RENAL CELL CARCINOMA 2, RCCP2)) AND ANTI-(HOMO SAPIENS EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB)), HOMO SAPIENS MONOCLONAL ANTIBODY, BISPECIFIC, CONJUGATED ON 6 CYSTEINYL RESIDUES TO SAMROTECAN - Common Name
• TILATAMIG SAMROTECAN - Common Name
• TILATAMIG SAMROTECAN [INN] - Common Name
• TILATAMIG SAMTOTECAN [USAN] - Common Name

Common Chemistry

CAS Common Chemistry is an open community resource of the American Chemical Society for accessing chemical information. The chemical information in the CAS database is curated by expert scientists and includes information of common and frequently regulated chemicals and information applicable to high school and undergraduate chemistry classes.

Inxight Drugs

The National Center for Advancing Translational Sciences (NCATS) Inxight Drugs database has a comprehensive drug development information. The NCATS Inxight Drugs includes manually curated data provided by private companies and FDA. The database has marketing and regulatory status information, rigorous drug ingredient definitions, biological activity, clinical use, etc.

DailyMed Regulated Products

The National Library of Medicine DailyMed is a searchable database that includes the most recent product labeling information submitted to the FDA by private companies.

NCATS GSRS Full Record

The Global Substance Registration System (GSRS) was designed to facilitate global monitoring of human and animal medicinal, food, tobacco, and cosmetic products. GSRS includes unique substance identifiers consistent with the ISO 11238 standard.

NCI Thesaurus

NCI Thesaurus (NCIt) by the National Cancer Institute provides reference terminology for clinical care, translational and basic research, and public information and administrative activities.