DOROCUBICEL
UNII DBD2HM3I4V

Substance Identification & Data

This profile provides standardized clinical and technical data for Dorocubicel, uniquely identified by the FDA Unique Ingredient Identifier (UNII) DBD2HM3I4V.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number N/A and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

DBD2HM3I4V

CAS Registry Number

N/A

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

DOROCUBICEL

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C203130

National Cancer Institute reference terminology for clinical and research data.

INN ID

12158

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

MN-172

Identifier assigned by the United States Adopted Names Council.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

ITIS TSN

180092

Taxonomic Serial Number for species identified in the Integrated Taxonomic Information System.

NCBI Taxonomy

9606

Unique numeric identifier used to specify biological species in the NCBI database.

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Dorocubicel. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

DOROCUBICEL

Common Names & Synonyms

ALLOGENEIC HUMAN UMBILICAL CORD BLOOD DERIVED CD34+ HEMATOPOIETIC STEM AND PROGENITOR CELLS (HSPCS). THE CD34+ HSPC FRACTION IS SELECTED FROM CORD BLOOD AND EXPANDED EX VIVO IN SERUM-FREE GROWTH MEDIUM IN THE PRESENCE OF UM171 (TRANS-N1 -(2-BENZYL-7-(2-METHYL-2H-TETRAZOL-5-YL)-9H-PYRIMIDO(4,5-B)INDOL-4-YL)CYCLOHEXANE-1,4-DIAMINE) DIHYDROBROMIDE DIHYDRATE AND RECOMBINANT CYTOKINES SUCH AS STEM CELL FACTOR (SCF), FMS-RELATED TYROSINE KINASE 3 LIGAND (FLT3L), THROMBOPOIETIN (TPO) AND INTERLEUKIN-6 (IL-6). THE EXPANDED FRACTION PREDOMINANTLY CONSISTS OF HSPCS (CD34+ CD45RA-CELLS), WITH VARYING LEVELS OF DENDRITIC CELL PROGENITORS (CD34+ CD86+ CELLS), MAST CELL PROGENITORS (FC EPSILON RECEPTOR IA (FCER1A)+ CD117+ CELLS), AND OTHER CELL TYPES

ALLOGENEIC HUMAN UMBILICAL CORD BLOOD EXPANDED WITH UM-171

CORD BLOOD EXPANDED WITH UM-171

DOROCUBICEL [INN]

DOROCUBICEL [USAN]

HAEMATOPOIETIC STEM CELLS AND BLOOD PROGENITORS UMBILICAL CORD-DERIVED EXPANDED WITH UM171 ((1R, 4R)-N1-(2-BENZYL-7-(2-METHYL-2H-TETRAZOL-5-YL)-9H-PYRIMIDO(4,5-B)INDOL-4-YL)CYCLOHEXANE-1,4-DIAMINE DIHYDROBROMIDE). THE REAGENT USED FOR MN-172 IS KNOWN IN THE LITERATURE ONLY UNDER ITS CODE - UM171. IT IS USED IN MANIPULATION OF THE HEMATOPOIETIC CELLS TO ENHANCE THEIR SELF-RENEWAL. IT IS RECORDED AS A CHEMICAL IN DATABASES WITH THE CHEMICAL NAME OF: TRANS-N1-(2-BENZYL-7-(2-METHYL-2H-TETRAZOL-5-YL)-9H-PYRIMIDO(4,5-B)INDOL-4-YL)CYCLOHEXANE-1,4-DIAMINE DIHYDROBROMIDE DIHYDRATE

Technical Codes

ECT-001-CB

External Clinical & Regulatory Resources

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