LUMACAFTOR
UNII EGP8L81APK

Substance Identification & Data

This profile provides standardized clinical and technical data for Lumacaftor, uniquely identified by the FDA Unique Ingredient Identifier (UNII) EGP8L81APK.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 936727-05-8 and the RxNorm Concept ID (RxCUI) 1655922. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
EGP8L81APK
CAS Registry Number
936727-05-8
RxNorm Concept ID

Detailed Substance Profile

Preferred Name
LUMACAFTOR
Official standardized name for this substance within the FDA UNII nomenclature system.
Molecular Formula
EGP8L81APK
The specific atomic composition represented as a molecular structure string.
InChIKey
C24H18F2N2O5
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
UFSKUSARDNFIRC-UHFFFAOYSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
9449
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
XX-134
Identifier assigned by the United States Adopted Names Council.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
O=C(O)c1cccc(-c2c(C)ccc(NC(C3(c4ccc5OC(F)(F)Oc5c4)CC3)=O)n2)c1

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Lumacaftor. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

LUMACAFTOR

Common Names & Synonyms

BENZOIC ACID, 3-(6-(((1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPYL)CARBONYL)AMINO)-3-METHYL-2-PYRIDINYL)-
LUMACAFTOR [INN]
LUMACAFTOR [MI]
LUMACAFTOR [ORANGE BOOK]
LUMACAFTOR [USAN]
LUMACAFTOR [WHO-DD]

Brand / Trade Names

ORKAMBI COMPONENT LUMACAFTOR

Systematic Nomenclature

3-(6-(1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)CYCLOPROPANE-1-CARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID
3-(6-(1-(2,2-DIFLUOROBENZO(D) (1,3)DIOXYL-5-YL)CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZOIC ACID

Technical Codes

VRT826809
VRT-826809
VX809
VX-809

NDC Products Containing LUMACAFTOR

This unique ingredient identifier is listed as an ingredient or substance in the following products in the NDC directory: