LIBENUCGENE PARVEC
UNII EMR895S25C

Substance Identification & Data

This profile provides standardized clinical and technical data for Libenucgene Parvec, uniquely identified by the FDA Unique Ingredient Identifier (UNII) EMR895S25C.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 3044760-95-1 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
EMR895S25C
CAS Registry Number
3044760-95-1
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
LIBENUCGENE PARVEC
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C224758
National Cancer Institute reference terminology for clinical and research data.
INN ID
13801
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
structurallyDiverse
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Libenucgene Parvec. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

LIBENUCGENE PARVEC

Common Names & Synonyms

AAVRH79.TBG.M2PCSK9.WPRE.BGH
DNA (RECOMBINANT REPLICATION-DEFICIENT ADENO-ASSOCIATED VIRUS SEROTYPE RH79 VECTOR ECUR-506A HUMAN .ALPHA.1-MICROGLOBULIN-BIKUNIN PRECURSOR ENHANCER PLUS HUMAN THYROXINE BINDING GLOBULIN PROMOTER PLUS SIMIAN VIRUS 40 NUCLEAR LOCALIZATION SIGNAL PEPTIDE FUSION PROTEIN WITH SYNTHETIC MEGANUCLEASE M2PCSK9 CODON-OPTIMIZED TRANSGENE PLUS WOODCHUCK HEPATITIS VIRUS POST-TRANSCRIPTIONAL REGULATORY ELEMENT WPRE PLUS BOVINE GROWTH HORMONE POLYADENYLATION SIGNAL PLUS INVERTED TERMINAL REPEAT FLANKS)
LIBENUCGENE PARVEC [INN]
RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS SEROTYPE RH79 (RAAVRH79) VECTOR ENCODING A FUSION PROTEIN COMPRISING A SIMIAN VIRUS 40 (SV40) NUCLEAR LOCALIZATION SIGNAL (NLS) JOINED TO AN ENGINEERED MEGANUCLEASE (M2PCSK9) TARGETING A SPECIFIC 22-BASE PAIR SEQUENCE IN EXON 7 OF THE HUMAN PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) GENE. EXPRESSION OF THE TRANSGENE IS UNDER THE CONTROL OF A HUMAN THYROXINE BINDING GLOBULIN (TBG) PROMOTER AND TWO COPIES OF AN ALPHA 1-MICROGLOBULIN/BIKUNIN ENHANCER ELEMENT, A WOODCHUCK HEPATITIS VIRUS POST-TRANSCRIPTIONAL REGULATORY ELEMENT (WPRE) AND A BOVINE GROWTH HORMONE POLYADENYLATION SIGNAL. THE EXPRESSION CASSETTE IS FLANKED BY AAV2 INVERTED TERMINAL REPEAT

External Clinical & Regulatory Resources

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NCATS
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