MELREDABLEUKIN ALFA
UNII FAA3D9E2LP

Substance Identification & Data

This profile provides standardized clinical and technical data for Melredableukin Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) FAA3D9E2LP.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2056881-92-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

FAA3D9E2LP

CAS Registry Number

2056881-92-4

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

MELREDABLEUKIN ALFA

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C184904

National Cancer Institute reference terminology for clinical and research data.

INN ID

11723

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

KL-70

Identifier assigned by the United States Adopted Names Council.

Substance Type

MELREDABLEUKIN ALFA

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Melredableukin Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

MELREDABLEUKIN ALFA

Common Names & Synonyms

Immunoglobulin G1, (human monoclonal γ1-chain) fusion protein with peptide (synthetic linker) fusion protein with interleukin 2 (synthetic human mutein), disulfide with human monoclonal κ-chain, dimer

MELREDABLEUKIN ALFA [USAN]

human immunoglobulin G1 non-binding variant (heavy chain 1-444, L232>A, L233>A, P327>G) fused at the C-terminus of the heavy chain via peptidyl linker 445GGGGSGGGGSGGGGS459 to human interleukin 2 (1-133, 460- 592 in the current sequence) variant (T3 >A462, N88>D547, C125>A584), dimer, produced in Chinese hamster ovary (CHO) cells, glycoform alfa; human non-binding immunoglobulin G1 kappa (IgG1-κ) fused via a peptide linker to a mutated human interleukin 2 (IL2 mutein): fusion protein combining a gamma1 heavy chain (1-444) [Homo sapiens IGHV3-23*01; Homo sapiens IGHJ4*01; Homo sapiens IGHG1*01; VH: 1-115; CH1: 116-213; hinge: 214-228; CH2: 229-338 (L232>A, L233>A, P327>G); CH3: 339-443; CHS: 444-444 (K445del); CDR Kabat H1: SYAMS (31-35); CDR Kabat H2: AISGSGGSTYYADSVKG (50-66); CDR Kabat H3: GSGFDY (99- 104)], a (G4S)3 peptide linker (445-459), and Homo sapiens interleukin 2 (460-592) [T3 >A462, N88>D547, C125>A584]-variant, (218- 215')-disulfide with kappa light chain (1'-215') [Homo sapiens IGKV3-20*01; Homo sapiens IGKJ1*01; Homo sapiens IGKC*01; VL: 1-108; CL: 109-215; CDR Kabat L1: RASQSVSSSYLA (24-35); CDR Kabat L2: GASSRAT (51-57); CDR Kabat L3: QQYGSSPLT (90-98)]; dimer (224-224":227-227")-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

melredableukin alfa [INN]