GEPTANOLIMAB
UNII FME52R2SGN

Substance Identification & Data

This profile provides standardized clinical and technical data for Geptanolimab, uniquely identified by the FDA Unique Ingredient Identifier (UNII) FME52R2SGN.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2348469-43-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

FME52R2SGN

CAS Registry Number

2348469-43-0

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

GEPTANOLIMAB

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C148159

National Cancer Institute reference terminology for clinical and research data.

INN ID

11436

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Geptanolimab. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

GEPTANOLIMAB

Common Names & Synonyms

GENOLIMZUMAB

GEPTANOLIMAB [INN]

GEPTANOLIMAB [WHO-DD]

HUMANIZED IGG4 ANTIBODY DIRECTED AGAINST THE NEGATIVE IMMUNOREGULATORY HUMAN CELL SURFACE RECEPTOR PROGRAMMED CELL DEATH 1 (PD-1/PDCD1/PD1) WITH LOW ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY AND COMPLEMENT-DEPENDENT CYTOTOXICITY

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-440) (VH (HOMO SAPIENSIGHV7-4-1*02 (85.7%)-(IGHD)-IGHJ4*01 (100%)) CDR-IMGT (8.8.7) (26-33.51-58.97-103) (1-114)-HOMO SAPIENS IGHG4*01, G4V5 H P10 (CH1 (115-212), HINGE 1-12 S10>P (222) (213-224), CH2 (225-334), CH3 (335-439), CHS K>DEL (440) (115-440)), (28-217')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-217') (V-KAPPA (MUS MUSCULUS IGKV3-5*01 (89.9%)-IGKJ1*01 (90.9%)/HOMO SAPIENS IGKV3D-11*02 (64.9%)-IGKJ2*01 (100%)) CDR-IMGT (10.3.8) (27-36.54-56.93-100) (1'-110')-HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (156), V101 (194) (111'-217'))DIMER (220-220'':223-223'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO)-S CELL LINE, GLYCOFORM ALFA

MMUNOGLOBULIN G4 (232-PROLINE,DE-451-LYSINE), ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMAN-MUS MUSCULUS MONOCLONAL GB226 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GB226 .KAPPA.-CHAIN, DIMER