ARUMAKIMIG
UNII FWE2G0Y2W3
Substance Identification & Data
This profile provides standardized clinical and technical data for Arumakimig, uniquely identified by the FDA Unique Ingredient Identifier (UNII) FWE2G0Y2W3.
Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 3018901-76-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.
FWE2G0Y2W3
3018901-76-0
N/A
Detailed Substance Profile
Preferred Name
ARUMAKIMIG
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
INN ID
13493
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
Arumakimig
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Synonyms and Nomenclature
This section provides a complete list of nomenclature and identifier mappings for Arumakimig. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.
FDA Official Name
Arumakimig
Common Names & Synonyms
BI-SPECIFIC HUMANIZED MONOCLONAL ANTIBODY AGAINST HUMAN IL-1.BETA. AND HUMAN IL-18
H-gamma1 heavy chain anti-IL18 Homo sapiens (1-449) [VH (Homo sapiens IGHV1-69*01 (91.8%) -(IGHD) -IGHJ5*01 (92.9%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, 6-G1-v14 CH2 A1.3, A1.2, 14-G1v74 CH3 C10, 14-G1v32 CH3 W22 (knob) (CH1 R120 (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>A (237) (233-342), CH3 S10>C (356), E12 (358), M14 (360), T22>W (368) (343-447), CHS (448-449)) (120-449)], (222-215')-disulfide with L-lambda2 light chain anti-IL18 Homo sapiens (1'-216') [V-Lambda (Homo sapiens IGLV1-40*01 (88.3%) -IGLJ2*01 (100%), CDR-IMGT [8.3.11] (26'-33'.51'-53'.90'-100')) (1'-110') -Homo sapiens IGLC2*01 (100%) (C-LAMBDA2) (111'-216')] (H-gamma1 heavy chain anti-IL1B Homo sapiens (1''-448'') [VH (Homo sapiens IGHV3-30-5*03 (93.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26''-33''.51''-58''.97''-107'')) (1''-118'') -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, 6-G1v14 CH2 A1.3, A1.2, 14-G1v75 CH3 C5, 14-G1v33 CH3S22, A24, V86 (hole) (CH1 R120 (215'') (119''-216''), hinge 1-15 (217''-231''), CH2 L1.3>A (235''), L1.2>A (236'') (232''-341''), CH3 Y5>C (350''), E12 (357''), M14 (359''), T22>S (367''), L24>A (369''), Y86>V (408'') (342''-446''), CHS (447''-448'')) (119''-448'')], (221''-214''')-disulfide with L-kappa light chain anti-IL1B Homo sapiens (1'-214''') [V-Kappa (Homo sapiens IGKV6-21*01 (98.9%) -IGKJ3*01 (100%), CDR-IMGT [6.3.9] (27'''-32'''.50'''-52'''.89'''-97''')) (1'''-107''') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'''), V101 (191''')) (108'''-214''')]; dimer (228-227'':231-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa)
IgG-like bispecific monoclonal antibody (mAb) composed of the anti-IL-1beta mAb canakinumab and the anti-IL-18 mAb CMK389
Immunoglobulin G1 [236-alanine,237-alanine,356-cysteine,368-tryptophan], anti-(human interleukin 18) (human monoclonal RITM5902350 γ1-chain), (222→215′′)-disulfide with human monoclonal RITM5902350 λ2-chain, (228→227′),(231→230′),(356→350′)-tris(disulfide) with immunoglobulin G1 [235′-alanine,236′-alanine,350′-cysteine,367′-serine,369′-alanine,408′-valine] anti-(human interleukin-1β) (human monoclonal RITM5902350 γ1-chain), (221′→214′′′)-disulfide with human monoclonal RITM5902350 κ-chain
MAS 825 [WHO-DD]
arumakimig [INN]
immunoglobulin (H-gamma1_L-lambda2)_(H-gamma1_L-kappa), anti-[Homo sapiens IL18 (interleukin 18, IL-18, interferon gamma-inducing factor, IGIF, interleukin-1 gamma, IL-1G, IL1F4)] and anti-[Homo sapiens IL1B (interleukin 1 beta, IL-1B, 1L1F2)], Homo sapiens monoclonal antibody
Technical Codes
MAS-825
MAS825
