4-CHLORO-3-FLUORO AFATINIB
UNII G6YTK9H6LE

Substance Identification & Data

This profile provides standardized clinical and technical data for 4-chloro-3-fluoro Afatinib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) G6YTK9H6LE.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2475094-87-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
G6YTK9H6LE
CAS Registry Number
2475094-87-0
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
4-CHLORO-3-FLUORO AFATINIB
Official standardized name for this substance within the FDA UNII nomenclature system.
InChIKey
C24H25ClFN5O3
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
CIGJZGGVLAOLAG-CWDCEQMOSA-N
Line notation for describing the chemical structure and connectivity of atoms.
PubChem CID
154631180
Unique identification number in the NCBI database of chemical substances.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
N(c1c2c(cc(O[C@H]3CCOC3)c(NC(/C=C/CN(C)C)=O)c2)ncn1)c4cc(F)c(Cl)cc4

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for 4-chloro-3-fluoro Afatinib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

Common Names & Synonyms

4-CHLORO-3-FLUORO AFATINIB
AFATINIB IMPURITY G
N-(4-((4-CHLORO-3-FLUOROPHENYL)AMINO)-7-(((3S)-TETRAHYDRO-3-FURANYL)OXY)-6-QUINAZOLINYL)-4-(DIMETHYLAMINO)-2-BUTENAMIDE

Systematic Nomenclature

(2E)-N-(4-((4-CHLORO-3-FLUOROPHENYL)AMINO)-7-(((3S)-TETRAHYDRO-3-FURANYL)OXY)-6-QUINAZOLINYL)-4-(DIMETHYLAMINO)-2-BUTENAMIDE
(S,E)-N-(4-((4-CHLORO-3-FLUOROPHENYL)AMINO)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)-4-(DIMETHYLAMINO)BUT-2-ENAMIDE
2-BUTENAMIDE, N-(4-((4-CHLORO-3-FLUOROPHENYL)AMINO)-7-(((3S)-TETRAHYDRO-3-FURANYL)OXY)-6-QUINAZOLINYL)-4-(DIMETHYLAMINO)-
2-BUTENAMIDE, N-(4-((4-CHLORO-3-FLUOROPHENYL)AMINO)-7-(((3S)-TETRAHYDRO-3-FURANYL)OXY)-6-QUINAZOLINYL)-4-(DIMETHYLAMINO)-, (2E)-

External Clinical & Regulatory Resources

CAS
Common Chemistry
NCATS
Inxight Drugs
NLM
DailyMed Products
NCATS
GSRS Full Record
NLM
PubChem Compound