ZAREPRUMIG
UNII G9Z2D6DRW9
Substance Identification & Data
This profile provides standardized clinical and technical data for Zareprumig, uniquely identified by the FDA Unique Ingredient Identifier (UNII) G9Z2D6DRW9.
Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 3062698-53-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.
G9Z2D6DRW9
3062698-53-4
N/A
Detailed Substance Profile
Preferred Name
ZAREPRUMIG
Official standardized name for this substance within the FDA UNII nomenclature system.
INN ID
13958
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
Zareprumig
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Synonyms and Nomenclature
This section provides a complete list of nomenclature and identifier mappings for Zareprumig. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.
FDA Official Name
Zareprumig
Common Names & Synonyms
H-gamma1 heavy chain anti-MS4A1 hole (H) (1-449) [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, 17-G1v57 CH1 E26, E119, 6-G1v14-49 CH2 A1.3, A1.2, G114, 14-G1v75 CH3 C5, 14-G1v33 CH3 S22, A24, V86 (hole) (CH1 K120 (216), K26>E (149), K119>E (215) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>A (237), P114>G (331) (233-342), CH3 Y5>C (351), D12 (358), L14 (360), T22>S (368), L24>A (370), Y86>V (409) (343-447), CHS (448-449)) (120-449)], (222-219')-disulfide with L-kappa light chain anti-MS4A1 (L') (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV2-109*01 (90.0%) -IGKJ2*01 (91.7%) L124>V (109')/Homo sapiens IGKV2-28*01 (87.0%) -IGKJ4*01 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (98.1%) Km3 A45.1, V101, 17-KCv57 R12, K13 (C-KAPPA E12>R (128'), Q13>K (129'), A45.1 (158'), V101 (196')) (113'-219')]; fused heavy chain bispecific H-gamma1 anti-MS4A1 knob -VH-C-kappa anti-TFRC (H'') (1''-695'') [H-gamma1 heavy chain anti-MS4A1 knob (1''-448'') [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.12] (26''-33''.51''-58''.97''-108'')) (1''-119'') -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, 17-G1v57 CH1 E26, E119, 6-G1v14-49 CH2 A1.3, A1.2, G114, 14-G1v74 CH3 C10, 14-G1v32 CH3 W22 (knob) (CH1 K120 (216), K26>E (149), K119>E (215) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>A (237), P114>G (331) (233-342), CH3 S10>C (356''), D12 (358''), L14 (360''), T22>W (368'') (343''-447''), CHS K2>del (448'')) (120''-448'')] -18-mer bisglycyl-seryl-tris(tetraglycyl-seryl) linker (449''-466'') -VH-C-kappa anti-TFRC (467''-695'') [VH (Homo sapiens IGHV4-31*02 (76.0%) -IGHD -IGHJ5*02 (100%), CDR-IMGT [8.7.19] (491''-498''.516''-522''.559''-577'')) (467''-588'') -Homo sapiens IGKC*01 (99.1%) Km3 A45.1, V101, 12-KCv96 A1.4, S1.3 (C-KAPPA R1.4>A (589''), T1.3>S (590''), A45.1 (634''), V101 (672'')) (589''-695'')]], (222''-219''')-disulfide with L-kappa light chain anti-MS4A1 (L''') (1'''-219''') [V-KAPPA Musmus/Homsap (Mus musculus IGKV2-109*01 (90.0%) -IGKJ2*01 (91.7%) L124>V (109''')/Homo sapiens IGKV2-28*01 (87.0%) -IGKJ4*01 (100%), CDR-IMGT [11.3.9] (27'''-37'''.55'''-57'''.94'''-102''')) (1'''-112''') -Homo sapiens IGKC*01 (98.1%) Km3 A45.1, V101 17-KCv57 R12, K13 (C-KAPPA E12>R (128'''), Q13>K (129'''), A45.1 (158'''), V101 (196''')) (113'''-219''')], (695''-215'''')-disulfide with V-kappa-CH1 light chain anti-TFRC (L'''') (1''''-215'''') [V-KAPPA (Homo sapiens IGKV1-9*03 (96.7%) -IGKJ4*01 (100%), CDR-IMGT [6.3.12] (27''''-32''''.50''''-52''''.89''''-100'''')) (1''''-110'''') -2-mer bis(seryl) linker (111''''-112'''') -Homo sapiens IGHG1*01 CH1 hinge1-5, G1m17 CH1 K120 (209'''') (113''''-210''''), hinge 1-5 (211''''-215'''')) (113''''-215'''')]; dimer (228-228'':231-231'':351-356'')-trisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell
Immunoglobulin G1 [149-glutamic acid,215-glutamic acid,236-alanine,237-alanine,331-glycine,356-cysteine,368-tryptophan,de-449-lysine], anti-(human CD20 antigen) (human-Mus musculus monoclonal RG6035 γ1-chain) fusion protein with peptide linker GGS(GGGGS)3 fusion protein with immunoglobulin G1 anti-(human transferrin receptor 1) (human-Oryctolagus cuniculus monoclonal RG6035 VH-CH1 fragment) disulfide with human-Oryctolagus cuniculus monoclonal RG6035 κ-chain, (228 →228′),(231→231′),(356→351′)-tris(disulfide) with immunoglobulin G1 [149′-glutamic acid,215′-glutamic acid,236′-alanine,237′-alanine,331′-glycine,351′-cysteine,368′-serine,370′-alanine,409′-valine] anti-(human CD20 antigen) (human-Mus musculus monoclonal RG6035 γ1-chain), disulfide with human-Mus musculus monoclonal RG6035 κ-chain [128-arginine,129-lysine]
immunoglobulin (H-gamma1_L-kappa)_[(H-gamma1-VH-C-kappa_V-kappa-CH1)_L-kappa], anti-[Homo sapiens MS4A1 (membrane-spanning 4-domains subfamily A member 1, CD20)], anti-[Homo sapiens TFRC (transferrin receptor, TfR1, TFR1, CD71)], monoclonal antibody, bispecific, trivalent (zareprumig)
zareprumig [INN]
Technical Codes
RO-7121932
RO7121932
