ZEVORCABTAGENE AUTOLEUCEL
UNII GMV2GFP3G2

Substance Identification & Data

This profile provides standardized clinical and technical data for Zevorcabtagene Autoleucel, uniquely identified by the FDA Unique Ingredient Identifier (UNII) GMV2GFP3G2.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number N/A and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

GMV2GFP3G2

CAS Registry Number

N/A

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

ZEVORCABTAGENE AUTOLEUCEL

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C165507

National Cancer Institute reference terminology for clinical and research data.

INN ID

11704

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

HI-221

Identifier assigned by the United States Adopted Names Council.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

ITIS TSN

180092

Taxonomic Serial Number for species identified in the Integrated Taxonomic Information System.

NCBI Taxonomy

9606

Unique numeric identifier used to specify biological species in the NCBI database.

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Zevorcabtagene Autoleucel. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ZEVORCABTAGENE AUTOLEUCEL

Common Names & Synonyms

AUTOLOGOUS ANTI-BCMA-CAR-4-1BB-CD3ZETA-EXPRESSING T-CELLS CT053

PREPARATION OF AUTOLOGOUS T-LYMPHOCYTES THAT HAVE BEEN TRANSDUCED WITH A VECTOR EXPRESSING A CHIMERIC ANTIGEN RECEPTOR (CAR) CONTAINING A HUMANIZED SINGLE CHAIN VARIABLE FRAGMENT (SCFV) SPECIFIC FOR THE TUMOR-ASSOCIATED ANTIGEN (TAA) B-CELL MATURATION ANTIGEN (BCMA; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17; TNFRSF17) THAT IS FUSED TO THE CO-STIMULATORY DOMAIN OF 4-1BB (CD137) AND THE T-CELL RECEPTOR SIGNALING DOMAIN OF CD3ZETA (CD3Z), WITH POTENTIAL IMMUNOSTIMULATING AND ANTINEOPLASTIC ACTIVITIES. UPON ADMINISTRATION, THE AUTOLOGOUS ANTI-BCMA-CAR-4-1BB-CD3ZETA-EXPRESSING T-CELLS CT053 SPECIFICALLY RECOGNIZE AND INDUCE SELECTIVE TOXICITY AGAINST BCMA-EXPRESSING TUMOR CELLS.

ZEVORCABTAGENE AUTOLEUCEL [INN]

ZEVORCABTAGENE AUTOLEUCEL [USAN]

ZEVORCABTAGENE AUTOLEUCEL [WHO-DD]