POLFURMETINIB
UNII GST8GSH94B

Substance Identification & Data

This profile provides standardized clinical and technical data for Polfurmetinib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) GST8GSH94B.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2845151-86-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
GST8GSH94B
CAS Registry Number
2845151-86-0
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
POLFURMETINIB
Official standardized name for this substance within the FDA UNII nomenclature system.
InChIKey
C18H20FN3O4S
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
TURWFFGYNJNSFK-UHFFFAOYSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
13767
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
MN-217
Identifier assigned by the United States Adopted Names Council.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
c1c(SC)ccc(c1F)Nc2c3C(=O)N(OCCO)CCc3cc(n2C)=O

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Polfurmetinib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

POLFURMETINIB

Common Names & Synonyms

POLFURMETINIB [INN]
POLFURMETINIB [USAN]

Systematic Nomenclature

2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONE, 8-((2-FLUORO-4-(METHYLTHIO)PHENYL)AMINO)-3,4-DIHYDRO-2-(2-HYDROXYETHOXY)-7-METHYL-
8-(2-FLUORO-4-(METHYLSULFANYL)ANILINO)-2-(2-HYDROXYETHOXY)-7-METHYL-3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONE

Technical Codes

ARRY-134
PF-07799544