NOTIRETATUG REZETECAN
UNII H423BH2FBA

Substance Identification & Data

This profile provides standardized clinical and technical data for Notiretatug Rezetecan, uniquely identified by the FDA Unique Ingredient Identifier (UNII) H423BH2FBA.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 3036556-53-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

H423BH2FBA

CAS Registry Number

3036556-53-0

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

NOTIRETATUG REZETECAN

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C200198

National Cancer Institute reference terminology for clinical and research data.

INN ID

13714

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

Notiretatug Rezetecan

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Notiretatug Rezetecan. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

Notiretatug Rezetecan

Common Names & Synonyms

H-gamma1 heavy chain Homo sapiens (1-455) [VH (Homo sapiens IGHV3-23*03 (95.9%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.7.19] (26-33.51-57.96-114)) (1-125) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (222) (126-223), hinge 1-15 (224-238), CH2 (239-348), CH3 D12 (364), L14 (366) (349-453), CHS (454-455)) (126-455)], (228-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (100%) -IGKJ5*01 (91.7%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (234-234'':237-237'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa; produced in Chinese hamster ovary (CHO) cells, glycoform alfa; substituted at the sulfur atoms of four L-cysteinyl residues on an average among 228, 234, 237, 214', 228'', 234'', 237'' and 214''' with (3RS)-1-[(2R,10S)-10-benzyl-2-cyclopropyl-1-{[(1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]amino}-1,6,9,12,15,18-hexaoxo-3-oxa-5,8,11,14,17-pentaazatricosan-23-yl]-2,5-dioxopyrrolidin-3-yl (rezetecan) groups

Immunoglobulin G1, anti-(human nectin-4) (human monoclonal HRP04949 γ1-chain), disulfide with human monoclonal HRP04949 κ-chain, dimer, reduced, tetrakis(thioether) with N-[6-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[[(1R)-1-cyclopropyl-2-[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-1-yl]amino]-2-oxoethoxy]methyl]glycinamide

immunoglobulin G1-kappa, anti-[Homo sapiens NECTIN4 (nectin-4, nectin cell adhesion molecule 4, PVRL4, poliovirus receptor-related 4, PPR4, LNIR)], Homo sapiens monoclonal antibody, conjugated on an average of four cysteinyl residues to rezetecan, comprising a linker and a camptothecin derivative (exatecan) (notiretatug rezetecan)

notiretatug rezetecan [INN]

External Clinical & Regulatory Resources

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