AMULIRAFUSP ALFA
UNII HFR7WU5YK7

Substance Identification & Data

This profile provides standardized clinical and technical data for Amulirafusp Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) HFR7WU5YK7.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2850355-94-9 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

HFR7WU5YK7

CAS Registry Number

2850355-94-9

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

AMULIRAFUSP ALFA

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C179653

National Cancer Institute reference terminology for clinical and research data.

INN ID

12963

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Amulirafusp Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

AMULIRAFUSP ALFA

Common Names & Synonyms

1-133-SIGNAL REGULATORY PROTEIN .ALPHA. (80-ALANINE) (HUMAN ISOFORM 4 VARIANT) FUSION PROTEIN WITH PEPTIDE LINKER ((GGGGS)2) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (445-ALANINE,530-ALANINE,531-ALANINE) ANTI-(HUMAN CD20 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IMM0306 .GAMMA.1-CHAIN) DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL IMM0306 .KAPPA.-CHAIN, DIMER

AMULIRAFUSP ALFA [INN]

HUMAN SIGNAL REGULATORY PROTEIN ALPHA (SIRP ALPHA VARIANT V2 EXTRACELLULAR D1 DOMAIN, SIRP ALPHA V2D1) FRAGMENT 31-163, COMPRISING THE FIRST TWO EXTRACELLULAR LOOPS OF THE D1 DOMAIN, (N110>A80)-VARIANT, ANTI-(HUMAN CD47, INTEGRIN ASSOCIATED PROTEIN (IAP)) (1-133 IN THE CURRENT SEQUENCE) FUSED VIA A (G4S) 2 PEPTIDE LINKER (134-143) TO GAMMA 1 HEAVY CHAIN (144-594) (VH (MUS MUSCULUS IGHV1-12*01 -(IGHD) -IGHJ1*01, CDR-KABAT (5.17.12)(174-178.193-209.242-253)) (144-264) -HOMO SAPIENS IGHG1*03(CH1 (265-362), HINGE (363-377), CH2 S445>A, E480>A, K 481>A (378-487), CH3 (488-592), CHS (593-594)) (265-594)), (367-213')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-213') (V-KAPPA (MUS MUSCULUS IGKV4-72*01 -IGKJ1*01, CDR-KABAT (10.7.9) (24'-33'.49'-55'.88'-96')) (1'-106') -HOMO SAPIENS IGKC*01 (107'-213')); DIMER (373-373'':376-376'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1, GLYCOFORM ALFA

HUMAN SIGNAL REGULATORY PROTEIN ALPHA (SIRP.ALPHA.) FRAGMENT, ANTI-(HUMAN CD47, INTEGRIN ASSOCIATED PROTEIN (IAP)), FUSED VIA A (G4>S)2PEPTIDE LINKER TO THE N-TERMINUS OF BOTH HEAVY CHAINS OF A CHIMERIC IMMUNOGLOBULIN G1-KAPPA ANTI-(HUMAN B-LYMPHOCYTE ANTIGEN CD20), GLYCOFORM ALFA

IMM 0306 [WHO-DD]

IMM0306 (BISPECIFIC ANTIBODY-TRAP SELECTIVELY TARGETING CD47 AND CD20)