ZICLUMERAN
UNII JJ5AS2HL3G

Substance Identification & Data

This profile provides standardized clinical and technical data for Ziclumeran, uniquely identified by the FDA Unique Ingredient Identifier (UNII) JJ5AS2HL3G.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2305431-29-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
JJ5AS2HL3G
CAS Registry Number
2305431-29-0
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
ZICLUMERAN
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
INN ID
12328
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
MN-129
Identifier assigned by the United States Adopted Names Council.
Substance Type
nucleicAcid
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Ziclumeran. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ZICLUMERAN

Common Names & Synonyms

CAS9 MRNA
CAS9 MRNA (MRNA000042)
MESSENGER RNA (MRNA), 5' CAPPED, ENCODING CODON-OPTIMISED CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS (CRISPR) ASSOCIATED PROTEIN 9 (CAS9), FLANKED BY UNTRANSLATED REGIONS (UTR) WITH SIGNIFICANT SEQUENCE HOMOLOGY TO THE XENOPUS BETA GLOBIN GENE, AND TERMINATED WITH A POLYADENYLATION (POLYA) TAIL. A KOZAK SEQUENCE PRECEDES THE OPEN READING FRAME AND THE 5' CAP IS A SYNTHETIC ANTI-REVERSE CAP ANALOGUE (ARCA); CONTAINS N1-METHYLPSEUDOURIDINE INSTEAD OF URIDINE (ALL-U>M1.PSI.)
RNA (RECOMBINANT 5'-(M7GM-(5'->5')-PPP-G)-CAPPED ALL URIDINE->N1-METHYLPSEUDOURIDINE-SUBSTITUTED SYNTHETIC CRISPR-ASSOCIATED ENDODEOXYRIBONUCLEASE CAS9 LOW CODON A-OPTIMIZED-SPECIFYING PLUS XENOPUS LAEVIS .BETA.-GLOBIN 5'-AND 3'-UNTRANSLATED FLANKING REGION-CONTAINING POLY(A)-TAILED MESSENGER)
ZICLUMERAN [INN]
ZICLUMERAN [USAN]

Technical Codes

NTLA-2001 COMPONENT MRNA000042