RELMACABTAGENE AUTOLEUCEL
UNII K5CXA4X5U8

Substance Identification & Data

This profile provides standardized clinical and technical data for Relmacabtagene Autoleucel, uniquely identified by the FDA Unique Ingredient Identifier (UNII) K5CXA4X5U8.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number N/A and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

K5CXA4X5U8

CAS Registry Number

N/A

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

RELMACABTAGENE AUTOLEUCEL

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C155878

National Cancer Institute reference terminology for clinical and research data.

INN ID

11372

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

ITIS TSN

180092

Taxonomic Serial Number for species identified in the Integrated Taxonomic Information System.

NCBI Taxonomy

9606

Unique numeric identifier used to specify biological species in the NCBI database.

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Relmacabtagene Autoleucel. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

RELMACABTAGENE AUTOLEUCEL

Common Names & Synonyms

AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) TRANSDUCED WITH A NONREPLICATIVE SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR ENCODING A CHIMERIC ANTIGEN RECEPTOR (CAR) CONSISTING OF THE HUMAN CD19-SPECIFIC SCFV, AN LGG4 HINGE REGION, CD28 TRANSMEMBRANE DOMAIN, CD137 (4-1BB) CO-STIMULATORY DOMAIN AND CD3 ZETA SIGNALLING DOMAIN, UNDER THE CONTROL OF A HYBRID ELONGATION FACTOR 1 ALPHA (EF1.ALPHA.) AND HUMAN T CELL LEUKEMIA VIRUS TYPE 1(HTLV-1) REGULATORY ELEMENT PROMOTER AND WOODCHUCK HEPATITIS VIRUS POST-TRANSCRIPTIONAL REGULATORY ELEMENT (WPRE). THE VECTOR GENOME ALSO ENCODES A TRUNCATED HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR (EGFRT) THAT IS CO-EXPRESSED WITH THE CAR AND CLEAVED FROM IT BY THE T2A SELF-CLEAVING PEPTIDE. THE VECTOR GENOME ALSO CONTAINS A SPLICE DONOR, A FRAGMENT OF GAG, A REV RESPONSE ELEMENT (RRE), A MUTATED CENTRAL POLYPURINE TRACT (CPPT), AND A SPLICE ACCEPTOR

RELMACABTAGENE AUTOLEUCEL [INN]

RELMACABTAGENE AUTOLEUCEL [WHO-DD]

RELMA-CEL