ENTRECTINIB
UNII L5ORF0AN1I

Substance Identification & Data

This profile provides standardized clinical and technical data for Entrectinib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) L5ORF0AN1I.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1108743-60-7 and the RxNorm Concept ID (RxCUI) 2197862. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
L5ORF0AN1I
CAS Registry Number
1108743-60-7
RxNorm Concept ID

Detailed Substance Profile

Preferred Name
ENTRECTINIB
Official standardized name for this substance within the FDA UNII nomenclature system.
Molecular Formula
L5ORF0AN1I
The specific atomic composition represented as a molecular structure string.
InChIKey
C31H34F2N6O2
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
HAYYBYPASCDWEQ-UHFFFAOYSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
10132
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
CD-95
Identifier assigned by the United States Adopted Names Council.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
c12ccc(cc1c(n[nH]2)NC(c3c(cc(cc3)N4CCN(CC4)C)NC5CCOCC5)=O)Cc6cc(cc(c6)F)F

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Entrectinib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ENTRECTINIB

Common Names & Synonyms

ENTRECTINIB [INN]
ENTRECTINIB [JAN]
ENTRECTINIB [MI]
ENTRECTINIB [ORANGE BOOK]
ENTRECTINIB [USAN]
ENTRECTINIB [WHO-DD]

Brand / Trade Names

ROZLYTREK

Systematic Nomenclature

BENZAMIDE, N-(5-((3,5-DIFLUOROPHENYL)METHYL)-1H-INDAZOL-3-YL)-4-(4-METHYL-1-PIPERAZINYL)-2-((TETRAHYDRO-2H-PYRAN-4-YL)AMINO)-
N-(5-(3,5-DIFLUOROBENZYL)-1H-INDAZOL-3-YL)-4-(4-METHYLPIPERAZIN-1YL)-2-(TETRAHYDRO-2H-PYRAN-4-YLAMINO)BENZAMIDE

Technical Codes

NMS-E628
RXDX-101

NDC Products Containing ENTRECTINIB

This unique ingredient identifier is listed as an ingredient or substance in the following products in the NDC directory: