CRIZANLIZUMAB
UNII L7451S9126

Substance Identification & Data

This profile provides standardized clinical and technical data for Crizanlizumab, uniquely identified by the FDA Unique Ingredient Identifier (UNII) L7451S9126.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1690318-25-2 and the RxNorm Concept ID (RxCUI) 2262279. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

L7451S9126

CAS Registry Number

1690318-25-2

RxNorm Concept ID

2262279

Detailed Substance Profile

Preferred Name

CRIZANLIZUMAB

Official standardized name for this substance within the FDA UNII nomenclature system.

Molecular Formula

L7451S9126

The specific atomic composition represented as a molecular structure string.

NCI Thesaurus

C133543

National Cancer Institute reference terminology for clinical and research data.

INN ID

10316

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

FG-105

Identifier assigned by the United States Adopted Names Council.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Crizanlizumab. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

CRIZANLIZUMAB

CRIZANLIZUMAB-TMCA

Common Names & Synonyms

CRIZANLIZUMAB [INN]

CRIZANLIZUMAB [MI]

CRIZANLIZUMAB [USAN]

CRIZANLIZUMAB [WHO-DD]

CRIZANLIZUMAB TMCA [WHO-DD]

Brand / Trade Names

ADAKVEO

Systematic Nomenclature

IMMUNOGLOBULIN G2, ANTI-(HUMAN P-SELECTIN) (HUMAN-MUS MUSCULUS MONOCLONAL SELG1 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL SELG1 LIGHT CHAIN, DIMER

SYS

IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS P-SELECTIN GLYCOPROTEIN LIGAND (CD62 ANTIGEN))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.2 HEAVY CHAIN (1-448) (HUMANIZED VH (HOMO SAPIENS IGHV1-8*01 (82%) (IGHD)-IGHJ4*01) (8.8.15) (1-122) -HOMO SAPIENS IGHG2*02 (CH2(K105>A(323))) (123-448)) (136-218')-DISULFIDE WITH .KAPPA. LIGHT CHAIN (1'-218') (HUMANIZED V-KAPPA (HOMO SAPIENS IGKV1-39*01 (87%) IGKJ4*01) (10.3.9) (1'-111') -HOMO SAPIENS IGKC*01 (112'-218')), DIMER (224-224'':225-225'':228-228'':231-231'')-TETRAKISDISULFIDE

SYS