RUBRAVAMERAN
UNII LEU6C3Q72D

Substance Identification & Data

This profile provides standardized clinical and technical data for Rubravameran, uniquely identified by the FDA Unique Ingredient Identifier (UNII) LEU6C3Q72D.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 3004804-43-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
LEU6C3Q72D
CAS Registry Number
3004804-43-4
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
RUBRAVAMERAN
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C215763
National Cancer Institute reference terminology for clinical and research data.
INN ID
13575
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
nucleicAcid
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Rubravameran. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

RUBRAVAMERAN

Common Names & Synonyms

RNA (RECOMBINANT 5'-(1,2-(M7G-(5'->5')-PPP-GM))-CAPPED ALL CYTIDINE->5-METHYLCYTIDINE-SUBSTITUTED VENEZUELAN EQUINE ENCEPHALITIS VIRUS NONSTRUCTURAL PROTEIN PRECURSOR FUSION WITH SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN XBB.1.5 VARIANT RECEPTOR-BINDING DOMAIN FUSION WITH INFLUENZA HEMAGGLUTININ TRANSMEMBRANE DOMAIN PLUS PAN DR-BINDING EPITOPE CODON-OPTIMIZED TRANSGENE PLUS 5'- AND 3'-UNTRANSLATED FLANKING REGION-CONTAINING POLY(A)-TAILED MESSENGER VLPC06), INNER SALT
RUBRAVAMERAN [INN]
SELF-AMPLIFYING MESSENGER RNA (MRNA), 5'-CAPPED, ENCODING VENEZUELAN EQUINE ENCEPHALITIS VIRUS (VEEV; STRAIN TC-83) RNA-DEPENDENT RNA POLYMERASE COMPLEX (VEEV NON-STRUCTURAL PROTEINS 1-4 (NSP1, NSP2, NSP3 AND NSP4)) AND A CODON-OPTIMISED RECEPTOR BINDING DOMAIN (RBD) OF THE SARS-COV-2 (SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2) SPIKE (S) GLYCOPROTEIN (OMICRON XBB.1.5 VARIANT DERIVED FROM GENBANK ID: OQ054680.1; AMINO ACIDS 323-527), PRECEDED BY THE SARS-COV-2 SIGNAL PEPTIDE AND FUSED TO AN H1N1 INFLUENZA VIRUS HEMAGGLUTININ TRANSMEMBRANE DOMAIN AND A UNIVERSAL (PAN) HLA DR-BINDING EPITOPE (PADRE), FLANKED BY VEEV 5' AND 3' UNTRANSLATED REGIONS (UTRS) AND TERMINATED WITH A 3' POLYADENYLATION (POLYA) TAIL; CONTAINS 5-METHYLCYTOSINE INSTEAD OF CYTOSINE (ALL-C>5MC). GENERATION OF THE SARS-COV-2 RBD MRNA IS UNDER CONTROL OF THE VEEV SUBGENOMIC PROMOTER

External Clinical & Regulatory Resources

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