AFIMKIBART
UNII LNU830UGAX

Substance Identification & Data

This profile provides standardized clinical and technical data for Afimkibart, uniquely identified by the FDA Unique Ingredient Identifier (UNII) LNU830UGAX.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2911580-96-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

LNU830UGAX

CAS Registry Number

2911580-96-4

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

AFIMKIBART

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C211786

National Cancer Institute reference terminology for clinical and research data.

INN ID

13205

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

NO-183

Identifier assigned by the United States Adopted Names Council.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Afimkibart. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

AFIMKIBART

Common Names & Synonyms

AFIMKIBART [INN]

AFIMKIBART [USAN]

AFIMKIBART [WHO-DD]

H-GAMMA1 HEAVY CHAIN HOMO SAPIENS (1-453) (VH (HOMO SAPIENS IGHV1-18*01 (92.9%) -(IGHD) -IGHJ3*01 (92.3%) M123>T (119), CDR-IMGT (8.8.17) (26-33.51-58.97-113)) (1-124) -HOMO SAPIENS IGHG1*03V, G1M3>G1M17, NG1M1 CH1 K120, CH3 E12, M14, G1V14-1 CH2 A1.3, A1.2, A1 (CH1 R120>K (221) (125-222), HINGE 1-15 (223-237), CH2 L1.3>A (241), L1.2>A (242), G1>A (244)(238-347), CH3 E12 (363), M14 (365) (348-452), CHS K2>DEL (453)) (125-453)), (227-214')-DISULFIDE WITH L-KAPPA LIGHT CHAIN HOMO SAPIENS (1'-214') (V-KAPPA (HOMO SAPIENS IGKV3-11*01 (100%) -IGKJ1*01 (100%), CDR-IMGT (6.3.9) (27'-32'.50'-52'.89'-97')) (1'-107') -HOMO SAPIENS IGKC*01 (100%) KM3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')); DIMER (233-233'':236-236'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1SV LACKING THE GLUTAMINE SYNTHETASE (GS-KO) GENE, GLYCOFORM ALFA

IMMUNOGLOBULIN G1 (241-ALANINE,242-ALANINE,244-ALANINE,DE-C-TERMINAL-LYSINE), ANTI-(HUMAN TUMOR NECROSIS FACTOR SUPERFAMILY PROTEIN TNFSF15) (HUMAN MONOCLONAL RVT-3101 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL RVT-3101 .KAPPA.-CHAIN, DIMER

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TNFSF15 (TUMOR NECROSIS FACTOR (TNF) SUPERFAMILY MEMBER 15, VASCULAR ENDOTHELIAL CELL GROWTH INHIBITOR, VEGI, VEGI192A, TNF SUPERFAMILY LIGAND TL1A)), HOMO SAPIENS MONOCLONAL ANTIBODY