TIRABRUTINIB
UNII LXG44NDL2T

Substance Identification & Data

This profile provides standardized clinical and technical data for Tirabrutinib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) LXG44NDL2T.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1351636-18-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
LXG44NDL2T
CAS Registry Number
1351636-18-4
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
TIRABRUTINIB
Official standardized name for this substance within the FDA UNII nomenclature system.
InChIKey
C25H22N6O3
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
SEJLPXCPMNSRAM-GOSISDBHSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
10320
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
LM-62
Identifier assigned by the United States Adopted Names Council.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
c1(c2c(ncn1)n(c(n2-c3ccc(cc3)Oc4ccccc4)=O)[C@@H]5CCN(C5)C(C#CC)=O)N

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Tirabrutinib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

TIRABRUTINIB

Common Names & Synonyms

TIRABRUTINIB [INN]
TIRABRUTINIB [USAN]
TIRABRUTINIB [WHO-DD]

Systematic Nomenclature

6-AMINO-9-((3R)-1-(BUT-2-YNOYL)PYRROLIDIN-3-YL)-7-(4-PHENOXYPHENYL)-7,9-DIHYDRO-8H-PURIN-8-ONE
8H-PURIN-8-ONE, 6-AMINO-7,9-DIHYDRO-9-((3R)-1-(1-OXO-2-BUTYN-1-YL)-3-PYRROLIDINYL)-7-(4-PHENOXYPHENYL)-

Technical Codes

GS-4059
ONO-4059
ONO-4059(FREE BASE)