GULGAFAFUSP ALFA
UNII LYK65H95KT

Substance Identification & Data

This profile provides standardized clinical and technical data for Gulgafafusp Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) LYK65H95KT.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2642374-02-3 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

LYK65H95KT

CAS Registry Number

2642374-02-3

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

GULGAFAFUSP ALFA

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C199206

National Cancer Institute reference terminology for clinical and research data.

INN ID

12332

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Gulgafafusp Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

GULGAFAFUSP ALFA

Common Names & Synonyms

GULGAFAFUSP ALFA [INN]

HUMANIZED MONOCLONAL ANTIBODY FUSION WITH HUMAN GLUCAGON-LIKE PEPTIDE 1 (GLP1); TYPE: IGG2-KAPPA; ANTIGEN: HUMAN GLUCAGON-LIKE PEPTIDE 1 RECEPTOR, GLP-1 RECEPTOR, GLP-1-R, GLP-1R (GLP1R); CDR SOURCE: MUS MUSCULUS (HUMANIZED BY KABAT CDR GRAFTING); HEAVY CHAIN CLASS: GAMMA2; HEAVY CHAIN LENGTH: 451; HV GERMLINE: HOMO SAPIENS IGHV3-33*01; HJ GERMLINE: HOMO SAPIENS IGHJ6*01; HC GERMLINE: HOMO SAPIENS IGHG2*01; VH: 1-125; CH1: 126-223; HINGE: 224-235; CH2: 236-344; CH3:345-449 (S382A, NON-FUNCTIONAL MUTATION); CHS: 450-451; CDR KABAT H1: SYGMH (31-35); CDR KABAT H2: VIWYDGSNKYYADSVKG (50-66); CDR KABAT H3: GGGSGSYRYYYYGLDV (99-114); FUSION PROTEIN: 1-29 (HUMAN 7-35 GLUCAGON-LIKE PEPTIDE-1); LINKER: 30-52; LIGHT CHAIN CLASS: KAPPA; LIGHT CHAIN LENGTH: 266; LV GERMLINE: HOMO SAPIENS IGKV1-12*01; LJ GERMLINE: HOMO SAPIENS IGKJ1*01; LC GERMLINE: HOMO SAPIENS IGKC*01; VL: 53-159; CL: 160-266; CDR KABAT L1: RASQNINNLLA (76-86); CDR KABAT L2: TASSLQS (102-108); CDR KABAT L3:QQAHRFPPT (141-149)

IMMUNOGLOBULIN G2, ANTI-(HUMAN GLUCAGON-LIKE PEPTIDE-1 RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL GMA102 .GAMMA.2-CHAIN), DISULFIDE WITH 1-29-GLUCAGON-LIKE PEPTIDE-1 (HUMAN) FUSION PROTEIN WITH PEPTIDE LINKER (GSGSATGGSGSGASSGSGSATGS) FUSION PROTEIN WITH HUMAN-MUS MUSCULUS MONOCLONAL GMA102 .KAPPA.-CHAIN, DIMER

Technical Codes

GMA102

GMA-102

External Clinical & Regulatory Resources

Previous UNIILYJ3482CB6

Next UNIILYK8UDP7Q4