LUCORAFUSP ALFA
UNII M55KSH2AGH

Substance Identification & Data

This profile provides standardized clinical and technical data for Lucorafusp Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) M55KSH2AGH.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2769742-99-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

M55KSH2AGH

CAS Registry Number

2769742-99-4

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

LUCORAFUSP ALFA

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C198990

National Cancer Institute reference terminology for clinical and research data.

INN ID

12728

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Lucorafusp Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

Common Names & Synonyms

GAMMA 4 HEAVY CHAIN (1-447) (VH (HOMO SAPIENS IGHV4-30-4*01 -(IGHD) -IGHJ4*01, CDR-KABAT (6.16.12) (31-36.51-66.99-110)) (1-121) -HOMO SAPIENS IGHG4*01 (CH1 (122-219), HINGE S229>P (220-231), CH2 F235>A, L236>A (232-341), CH3 (342-446), CHS K448>DEL (447)) (122-447)) FUSED VIA A (G4S)4 PEPTIDE LINKER (448-467) TO HUMAN TGF-BETA RECEPTOR TYPE-2 (TGFR-2, TGFBR2, TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE II, TGF.BETA. TYPE II RECEPTOR, TGF.BETA.RII) EXTRACELLULAR DOMAIN FRAGMENT 23-159, (1-137 OF THE MATURE PROTEIN) (T23>G468, S31>T476)-VARIANT (468-604 IN THE CURRENT SEQUENCE), (135-214')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-214') (V-KAPPA (HOMO SAPIENS IGKV1-39*01 -IGKJ1*01, CDR-KABAT (11.7.9) (24'-34'.50'-56'.89'-97')) (1'-107') -HOMO SAPIENS IGKC*01 (108'-214')); DIMER (227-227'':230-230'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA

HUMANIZED IMMUNOGLOBULIN G4-KAPPA, ANTI-(HUMAN TIGIT (T CELL IMMUNORECEPTOR WITH IG DOMAIN AND ITIM, V-SET IG MEMBER 9, VSIG9, V-SET AND TRANSMEMBRANE MEMBER 3, VSTM3)) FUSED AT THE C-TERMINUS OF THE HEAVY CHAIN, VIA A (G4S)4 PEPTIDE LINKER, TO A FRAGMENT OF THE MATURE EXTRACELLULAR DOMAIN OF HUMAN TGF-BETA RECEPTOR TYPE-2, GLYCOFORM ALFA

IMMUNOGLOBULIN G4 (229-PROLINE,235-ALANINE,236-ALANINE,476-THREONINE,DE-468-LYSINE), ANTI-(HUMAN RECEPTOR TIGIT) (HUMAN-MUS MUSCULUS MONOCLONAL AK130 .GAMMA.4-CHAIN) FUSION PROTEIN WITH PEPTIDE LINKER ((GGGGS)4G) FUSION PROTEIN WITH 2-137-TRANSFORMING GROWTH FACTOR .BETA. RECEPTOR 2 (9-THREONINE) (HUMAN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL AK130 .KAPPA.-CHAIN, DIMER

LUCORAFUSP ALFA

LUCORAFUSP ALFA [INN]