ONVUZOSIRAN
UNII MC7ZD4X9KB

Substance Identification & Data

This profile provides standardized clinical and technical data for Onvuzosiran, uniquely identified by the FDA Unique Ingredient Identifier (UNII) MC7ZD4X9KB.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2982817-49-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

MC7ZD4X9KB

CAS Registry Number

2982817-49-0

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

ONVUZOSIRAN

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C216047

National Cancer Institute reference terminology for clinical and research data.

INN ID

13361

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

OP-58

Identifier assigned by the United States Adopted Names Council.

Substance Type

Onvuzosiran

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Onvuzosiran. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

Onvuzosiran

Common Names & Synonyms

O-[(2R,3S)-2-(hydroxymethyl)oxolan-3-yl] hydrogen all-P-ambo-3'-O-(2-{[(1-{17-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-3,6,9,12,15-pentaoxaheptadecan-1-yl}-1H-1,2,3-triazol-4-yl)methyl]amino}-2-oxoethyl)-2'-O-(2-{bis[(1-{17-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-3,6,9,12,15-pentaoxaheptadecan-1-yl}-1H-1,2,3-triazol-4-yl)methyl]amino}-2-oxoethyl)-P-thiocytidylyl-(5'→5')-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-Omethylguanylyl-( 3'→5')-2'-O-methylguanylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-Omethyluridylyl-( 3'→5')-2'-O-methylguanylyl-(3'→5')-2'-Omethyladenylyl-( 3'→5')-2'-O-methyladenylyl-(3'→5')-2'-Omethyluridylyl-( 3'→5')-2'-O-methyluridylyl-(3'→5')-2'-Omethyladenylyl-( 3'→5')-2'-O-methyl-P-thiocytidylyl-(3'→5')-2'-Omethyl-P-thio-3'-adenylate duplex with all-P-ambo-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroguanylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxy-2'-fluorouridylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-deoxy-2'-fluorocytidylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxy-2'-fluoroguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluorocytidylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-deoxy-2'-fluorouridylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thioguanylyl-(5'→3')-2'-O-methyluridine

ONVUZOSIRAN [USAN]

RNA, ([3′-O-[2-[[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]-2′-O-[2-[bis[[1-[17-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]methyl]amino]-2-oxoethyl]]C-(5′→5′)-sp-Um-sp-Cm-Cm-Am-Gm-Gm-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-Um-Gm-Am-Am-Um-Um-Am-Cm-sp-Am-(3′→3′)-sp-[1′-de(6-amino-9H-purin-9-yl)]A), complex with RNA (Um-sp-(2′-deoxy-2′-fluoro)G-sp-Um-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)C-Am-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)G-Gm-(2′-deoxy-2′-fluoro)A-Gm-(2′-deoxy-2′-fluoro)C-Cm-(2′-deoxy-2′-fluoro)U-Gm-(2′-deoxy-2′-fluoro)G-Am-sp-Gm-sp-Um) (1:1)

onvuzosiran [INN]