VARSETATUG MASETECAN
UNII N2QWC7LB6W

Substance Identification & Data

This profile provides standardized clinical and technical data for Varsetatug Masetecan, uniquely identified by the FDA Unique Ingredient Identifier (UNII) N2QWC7LB6W.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 3036126-39-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

N2QWC7LB6W

CAS Registry Number

3036126-39-0

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

VARSETATUG MASETECAN

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C206677

National Cancer Institute reference terminology for clinical and research data.

INN ID

13675

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

Varsetatug Masetecan

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Varsetatug Masetecan. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

Common Names & Synonyms

H-gamma1 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-3*01 (81.6%) -(IGHD) -IGHJ6*01 (90.9%) T123>L (111), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 D12 (355), L14 (357) (340-444), CHS K2>del (445)) (117-445)], (219-265')-disulfide with L-kappa light chain humanized fused at its N-terminal end to a cleavable prodomain (1'-265') [prodomain (1'-46') -Homo sapiens V-KAPPA (Homo sapiens IGKV2D-29*02 (86.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (73'-83'.101'-103'.140'-148')) (47'-158') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (204'), V101 (242')) (159'-265')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa; substituted at the sulfur atoms of eight L-cysteinyl residues 219, 219'', 225, 225'', 228, 228'', 265', 265''' with (3RS)-1-{(9S,12S,15S)-1-[(4S)-4-ethyl-8-fluoro-4-hydroxy-9-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-11-yl]-9,12,15-trimethyl-3,8,11,14,17-pentaoxo-5-oxa-2,7,10,13,16-pentaazadocosan-22-yl}-2,5-dioxopyrrolidin-3-yl (masetecan) groups

Immunoglobulin G1 [de-446-lysine], anti-(human epithelial cell adhesion molecule) (human monoclonal CX-231 γ1-chain), complex with prodomain peptide (synthetic masking moiety and protease-cleavable moiety) fusion protein with human monoclonal CX-231 κ-chain, dimer, octakis(thioether) with N-[6-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)-1-oxohexyl]-L-alanyl-L-alanyl-N-[[2-[[[(4S)-4-ethyl-8-fluoro-3,4,12,14-tetrahydro-4-hydroxy-9-methyl-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-11-yl]methyl]amino]-2-oxoethoxy]methyl]-L-alaninamide

Varsetatug Masetecan

immunoglobulin G1-kappa, anti-[Homo sapiens EPCAM (epithelial cell adhesion molecule, tumor-associated calcium signal transducer 1, TACSTD1, gastrointestinal tumor-associated protein 2, GA733-2, epithelial glycoprotein 2, EGP-2, KSA, KS1/4 antigen, M4S1, tumor antigen 17-1A, Ep-CAM, EpCAM, CD326)], humanized monoclonal antibody with a cleavable prodomain of 46 amino acids fused at the N-terminal end of the L-kappa light chains; conjugated on eight cysteinyl residues to masetecan, comprising a cleavable linker and a camptothecin derivative (varsetatug masetecan)

varsetatug masetecan [INN]

External Clinical & Regulatory Resources

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