2'-O-(TERT-BUTYLDIMETHYLSILYL)-6.ALPHA.-HYDROXYPACLITAXEL
UNII NDV8NB8DM8

Substance Identification & Data

This profile provides standardized clinical and technical data for 2'-o-(tert-butyldimethylsilyl)-6.alpha.-hydroxypaclitaxel, uniquely identified by the FDA Unique Ingredient Identifier (UNII) NDV8NB8DM8.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 211732-86-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

NDV8NB8DM8

CAS Registry Number

211732-86-4

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

2'-O-(TERT-BUTYLDIMETHYLSILYL)-6.ALPHA.-HYDROXYPACLITAXEL

Official standardized name for this substance within the FDA UNII nomenclature system.

InChIKey

C53H65NO15Si

International Chemical Identifier digital signature for unique molecular identification.

SMILES String

ACJHNDYFTFXEOF-OPSZNNSQSA-N

Line notation for describing the chemical structure and connectivity of atoms.

PubChem CID

10931088

Unique identification number in the NCBI database of chemical substances.

Substance Type

chemical

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Ingredient Role

O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)c4ccccc4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)[C@H](O)[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)c6ccccc6)c7ccccc7)O[Si](C(C)(C)C)(C)C)=O)C5)[H]

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for 2'-o-(tert-butyldimethylsilyl)-6.alpha.-hydroxypaclitaxel. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

Systematic Nomenclature

(2AR,3S,4R,4AS,6R,9S,11S,12S,12AR,12BS)-6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-3,4,11-TRIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA(3,4)BENZ(1,2-B)OXET-9-YL (.ALPHA.R,.BETA.S)-.BETA.-(BENZOYLAMINO)-.ALPHA.-(((1,1-DIMETHYLETHYL)DIMETHYLSILYL)OXY)BENZENEPROPANOATE

SYS

2'-O-(TERT-BUTYLDIMETHYLSILYL)-6.ALPHA.-HYDROXYPACLITAXEL

SYS

BENZENEPROPANOIC ACID, .BETA.-(BENZOYLAMINO)-.ALPHA.-(((1,1-DIMETHYLETHYL)DIMETHYLSILYL)OXY)-, (2AR,3S,4R,4AS,6R,9S,11S,12S,12AR,12BS)-6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-3,4,11-TRIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA(3,4)BENZ(1,2-B)OXET-9-YL ESTER, (.ALPHA.R,.BETA.S)-

SYS

External Clinical & Regulatory Resources

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