ROLAPITANT
UNII NLE429IZUC

Substance Identification & Data

This profile provides standardized clinical and technical data for Rolapitant, uniquely identified by the FDA Unique Ingredient Identifier (UNII) NLE429IZUC.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 552292-08-7 and the RxNorm Concept ID (RxCUI) 1665496. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
NLE429IZUC
CAS Registry Number
552292-08-7
RxNorm Concept ID

Detailed Substance Profile

Preferred Name
ROLAPITANT
Official standardized name for this substance within the FDA UNII nomenclature system.
Molecular Formula
NLE429IZUC
The specific atomic composition represented as a molecular structure string.
InChIKey
C25H26F6N2O2
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
FIVSJYGQAIEMOC-ZGNKEGEESA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
8882
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
CD-170
Identifier assigned by the United States Adopted Names Council.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
[C@]12(CN[C@@](CC1)(c3ccccc3)CO[C@@H](c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C)NC(=O)CC2

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Rolapitant. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

ROLAPITANT

Common Names & Synonyms

ROLAPITANT [INN]
ROLAPITANT [MI]
ROLAPITANT [USAN]
ROLAPITANT [WHO-DD]

Systematic Nomenclature

(5S,8S)-8-(((1R)-1-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)ETHOXY)METHYL)-8-PHENYL-1,7-DIAZASPIRO(4.5)DECAN-2-ONE
1,7-DIAZASPIRO(4.5)DECAN-2-ONE, 8-(((1R)-1-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)ETHOXY)METHYL)-8-PHENYL-, (5S,8S)-

NDC Products Containing ROLAPITANT

This unique ingredient identifier is listed as an ingredient or substance in the following products in the NDC directory: