PIVODISGENE PARVEC
UNII NVQ25YNH8P

Substance Identification & Data

This profile provides standardized clinical and technical data for Pivodisgene Parvec, uniquely identified by the FDA Unique Ingredient Identifier (UNII) NVQ25YNH8P.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2648631-52-9 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
NVQ25YNH8P
CAS Registry Number
2648631-52-9
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
PIVODISGENE PARVEC
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C216049
National Cancer Institute reference terminology for clinical and research data.
INN ID
13471
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
structurallyDiverse
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Pivodisgene Parvec. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

PIVODISGENE PARVEC

Common Names & Synonyms

PIVODISGENE PARVEC [INN]
RECOMBINANT REPLICATION-DEFECTIVE ADENO-ASSOCIATED VIRUS 8 VECTOR RGX-202 SYNTHETIC PROMOTER SPC5-12 PLUS HUMAN CODON-OPTIMIZED MICRODYSTROPHIN VARIANT ABD1-H1-R1-R2-R3-H3-R24-H4-CR-CT194 PLUS SYNTHETIC POLYADENYLATION SIGNAL PLUS ADENO-ASSOCIATED VIRUS 2 INVERTED TERMINAL REPEAT FLANKS-SPECIFYING
RECOMBINANT, NON-REPLICATING ADENO-ASSOCIATED VIRUS SEROTYPE 8 (RAAV8) VECTOR, ENCODING A CODON-OPTIMISED MINIATURISED VERSION OF HUMAN DYSTROPHIN (MICRODYSTROPHIN VARIANT ABD1-H1-R1-R2-R3-H3-R24-H4-CR-CT194), UNDER CONTROL OF A SYNTHETIC MUSCLE-SPECIFIC PROMOTER (SPC5-12) AND A SMALL SYNTHETIC POLYADENYLATION SIGNAL; FLANKED BY AAV2 INVERTED TERMINAL REPEATS. THE EXPRESSED MICRODYSTROPHIN VARIANT CONTAINS THE ACTIN-BINDING DOMAIN 1 (ABD1), FOUR ROD DOMAINS (R1-3, R24), THREE HINGE DOMAINS (H1, H3, H4) AND A CYSTEINE RICH (CR) DOMAIN; IT ALSO FEATURES THE PROXIMAL PORTION OF THE C-TERMINAL DOMAIN, AMINO ACIDS 3361-3554 (CT194)
RGX-202 (AAV8.SPC5-12.MICRODYSTROPHIN)

External Clinical & Regulatory Resources

CAS
Common Chemistry
NCATS
Inxight Drugs
NLM
DailyMed Products
NCATS
GSRS Full Record
NIH
NCI Thesaurus