GAMCEMETINIB
UNII OS2IR8TV1O

Substance Identification & Data

This profile provides standardized clinical and technical data for Gamcemetinib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) OS2IR8TV1O.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1887069-10-4 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
OS2IR8TV1O
CAS Registry Number
1887069-10-4
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
GAMCEMETINIB
Official standardized name for this substance within the FDA UNII nomenclature system.
InChIKey
C22H20ClN5O3S
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
PYOQIOLRFIRRSO-LLVKDONJSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
12796
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
KL-199
Identifier assigned by the United States Adopted Names Council.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
c1(ncc(COCC)c(n1)Oc2nc3ccc4sc5C(=O)N[C@@H](CNc5c4c3cc2)C)Cl

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Gamcemetinib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

GAMCEMETINIB

Common Names & Synonyms

8H-(1,4)DIAZEPINO(5',6':4,5)THIENO(3,2-F)QUINOLIN-8-ONE, 3-((2-CHLORO-5-(ETHOXYMETHYL)-4-PYRIMIDINYL)OXY)-9,10,11,12-TETRAHYDRO-10-METHYL-, (10R)-
GAMCEMETINIB [INN]
GAMCEMETINIB [USAN]
GAMCEMETINIB [WHO-DD]

Systematic Nomenclature

(10R)-3-((2-CHLORO-5-(ETHOXYMETHYL)PYRIMIDIN-4-YL)OXY)-10-METHYL-9,10,11,12-TETRAHYDRO-8H-(1,4)DIAZEPINO(5',6':4,5)THIENO(3,2-F)QUINOLIN-8-ONE

Technical Codes

BMS-986371
CC-99677