LORLATINIB
UNII OSP71S83EU

Substance Identification & Data

This profile provides standardized clinical and technical data for Lorlatinib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) OSP71S83EU.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1454846-35-5 and the RxNorm Concept ID (RxCUI) 2103164. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

OSP71S83EU

CAS Registry Number

1454846-35-5

RxNorm Concept ID

2103164

Detailed Substance Profile

Preferred Name

LORLATINIB

Official standardized name for this substance within the FDA UNII nomenclature system.

Molecular Formula

OSP71S83EU

The specific atomic composition represented as a molecular structure string.

InChIKey

C21H19FN6O2

International Chemical Identifier digital signature for unique molecular identification.

SMILES String

IIXWYSCJSQVBQM-LLVKDONJSA-N

Line notation for describing the chemical structure and connectivity of atoms.

NCI Thesaurus

C113655

National Cancer Institute reference terminology for clinical and research data.

PubChem CID

71731823

Unique identification number in the NCBI database of chemical substances.

INN ID

10278

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

CD-57

Identifier assigned by the United States Adopted Names Council.

Substance Type

chemical

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Ingredient Role

[C@@H]1(C)c2cc(F)ccc2C(=O)N(C)Cc3nn(C)c(C#N)c3-c4cc(c(N)nc4)O1

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Lorlatinib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

LORLATINIB

Common Names & Synonyms

LORLATINIB [INN]

LORLATINIB [JAN]

LORLATINIB [MI]

LORLATINIB [ORANGE BOOK]

LORLATINIB [USAN]

LORLATINIB [WHO-DD]

Brand / Trade Names

LORBRENA

Systematic Nomenclature

(10R)-7-AMINO-12-FLUORO-2,10,16-TRIMETHYL-15-OXO-10,15,16,17-TETRAHYDRO-2H-4,8- METHENOPYRAZOLO(4,3-H)(2,5,11)BENZOXADIAZACYCLOTETRADECINE-3-CARBONITRILE

SYS

2H-4,8-METHENOPYRAZOLO(4,3-H)(2,5,11)BENZOXADIAZACYCLOTETRADECINE-3-CARBONITRILE, 7-AMINO-12-FLUORO-10,15,16,17-TETRAHYDRO-2,10,16-TRIMETHYL-15-OXO-, (10R)-

SYS