TOMARALIMAB
UNII P45C2W27DU

Substance Identification & Data

This profile provides standardized clinical and technical data for Tomaralimab, uniquely identified by the FDA Unique Ingredient Identifier (UNII) P45C2W27DU.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1449294-76-1 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

P45C2W27DU

CAS Registry Number

1449294-76-1

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

TOMARALIMAB

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C120554

National Cancer Institute reference terminology for clinical and research data.

INN ID

11044

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

FG-15

Identifier assigned by the United States Adopted Names Council.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Tomaralimab. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

TOMARALIMAB

Common Names & Synonyms

ANTI-TLR2 MONOCLONAL ANTIBODY OPN-305

HUMANIZED IGG4 MONOCLONAL ANTIBODY AGAINST TOLL-LIKE RECEPTOR 2 FOR PREVENTION OF ISCHEMIA/REPERFUSION TISSUE INJURY

TOMARALIMAB [INN]

TOMARALIMAB [USAN]

TOMARALIMAB [WHO-DD]

Systematic Nomenclature

IMMUNOGLOBULIN G4, ANTI-(HUMAN TOLL-LIKE RECEPTOR TLR-2) (HUMAN-MUS MUSCULUS MONOCLONAL OPN-305 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL OPN-305 LIGHT CHAIN, DIMER

SYS

IMMUNOGLOBULIN G4-KAPPA, ANTI-( HOMO SAPIENS TOLL-LIKE RECEPTOR 2 (CD282 ANTIGEN))HUMANIZED MOUSE MONOCLONAL ANTIBODY.GAMMA.4 HEAVY CHAIN (1-445) (MUS MUSCULUS VH (IGHV1-85*01 (82%) (IGHD)-IGHJ4*01 (86%)) (8.8.11) (1-118)-HOMO SAPIENS IGHG4*01 (HINGE(S10>P(226))) (119-445)) (132-218')-DISULFIDE WITH .KAPPA. LIGHT CHAIN (1'-218') (MUS MUSCULUS V-KAPPA (IGKV3-1*01 (82%) IGKJ1*01 (92%)(10.3.9) (1'-111')-HOMO SAPIENS IGKC*01 (112'-218')), DIMER (224-224'':227-227'')-BISDISULFIDE

SYS

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS TLR2 (TOLL LIKE RECEPTOR 2, TOLL-LIKE RECEPTOR 2, TIL4, CD282)), MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-445) (VH (MUS MUSCULUS IGHV1-85*01 (80.6%)-(IGHD)-IGHJ4*01 (85.7%)/HOMO SAPIENS IGHV1-8*03 (73.5%)-(IGHD)-IGHJ6*01 (85.7%)) (8.8.11) (1-118)-HOMO SAPIENS IGHG4*01 (CH1 (119-216), HINGE S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (118-445)), (132-218')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-218') (V-KAPPA (MUS MUSCULUS IGKV3-1*01 (81.8%)-IGKJ1*01 (91.7%)/HOMO SAPIENS IGKV3D-11*02 (70.2%)-(IGHD)-IGKJ4*01 (100%)) (10.3.9) (1'-111')-HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (157), V101 (195) (112'-218'))DIMER (224-224'':227-227'')-BISDISULFIDE

SYS

Technical Codes

OPN-305

External Clinical & Regulatory Resources

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