EMILTATUG LEDADOTIN
UNII PTB6AF3CSV
Substance Identification & Data
This profile provides standardized clinical and technical data for Emiltatug Ledadotin, uniquely identified by the FDA Unique Ingredient Identifier (UNII) PTB6AF3CSV.
Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2855974-40-0 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.
PTB6AF3CSV
2855974-40-0
N/A
Detailed Substance Profile
Preferred Name
EMILTATUG LEDADOTIN
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
INN ID
12944
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
Emiltatug Ledadotin
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Synonyms and Nomenclature
This section provides a complete list of nomenclature and identifier mappings for Emiltatug Ledadotin. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.
FDA Official Name
Emiltatug Ledadotin
Common Names & Synonyms
H-gamma1 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-53*01 (91.8%) -(IGHD) -IGHJ6*01 (93.8%), CDR-IMGT [8.7.10] (26-33.51-57.96-105)) (1-116) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 D12 (355), L14 (357) (340-444), CHS K2>del (445)) (117-445)], (219-216')-disulfide with L-kappa light chain Homo sapiens (1'-216') [V-KAPPA (Homo sapiens IGKV3-20*01 (100%) -IGKJ2*01 (100%), CDR-IMGT [7.3.10] (27'-33'.51'-53'.90'-99')) (1'-109') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (155'), V101 (193') (110'-216')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa; substituted at the side chain nitrogen atom of Lasparaginyl residues 296 and 296'' with a radical group consisting of 2-acetamido-[(5aRS,6SR,6aSR)-6-[(45S)-22,22-bis[(28S)-28-[(9S,14S)-9-carboxy-19-{[N,N-dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(2R,3R)-3-methoxy-2-methyl-3-[(2S)-pyrrolidin-2-yl]propanoyl-L-phenylalanyl]amino}-14-methyl-3,7,12,15-tetraoxo-2,16-dioxa-4,8,13-triazanonadecan-1-yl]-27,30,33,36,39,42,46-heptaoxo-2,5,8,11,14,17,20,23,49-nonaoxa-26,29,32,35,38,41,45-heptaazapentacontan-50-yl]-45-[(9S,14S)-9-carboxy-19-{[N,N-dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(2R,3R)-3-methoxy-2-methyl-3-[(2S)-pyrrolidin-2-yl]propanoyl-Lphenylalanyl] amino}-14-methyl-3,7,12,15-tetraoxo-2,16-dioxa-4,8,13-triazanonadecan-1-yl]-3,14,17,20,27,31,34,37,40,43,46-undecaoxo-2,7,10,24,50,53,56,59,62,65,68,71-dodecaoxa-4,13,18,21,28,32,35,38,41,45,47-undecaazadoheptacontan-1-yl]-1,4,5,5a,6,6a,7,8-octahydrocyclopropa[5,6]cycloocta[1,2-d][1,2,3]triazol-1-yl]-2,6-dideoxy-β-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-6-O-(H or 6-deoxy-α-Lgalactopyranosyl)-β-D-glucopyranosyl (ledadotin)
Immunoglobulin G1 [de-C-terminal-lysine], anti-(human B7 homolog protein B7H4) (human-Mus musculus monoclonal XMT-1604 γ-chain), disulfide with human-Mus musculus monoclonal XMT-1604 κ-chain, dimer, 297,297′-bis[N-[2-(acetylamino)-4-O-[2-(acetylamino)-6-azido-2,6-dideoxy-β-D-galactopyranosyl]-2-deoxy-6-O-R-β-D-glucopyranosyl]-L-asparagine], where R = (H or 6-deoxy-α-L-galactopyranosyl), click reaction product with N-[17-(1α,8α,9β)-bicyclo[6.1.0]non-4-yn-9-yl-1,4,15-trioxo-8,11,16-trioxa-5,14-diazaheptadec-1-yl]glycyl-3-[2-amino-3-hydroxy-2-(hydroxymethyl)propoxy]propanoyl-β-alanylglycylglycylglycylglycyl-O-carboxy-N-3,6,9,12,15,18,21,24-octaoxapentacos-1-yl-L-serinamide (2→1′),(2→1′′)-diether with N-(3-hydroxy-1-oxopropyl)-β-alanylglycylglycylglycylglycyl-O-carboxy-N-(3,6,9,12,15,18,21,24-octaoxapentacos-1-yl)-L-serinamide triamide with β-alanyl-L-γ-glutamyl-L-alanine 3-[3-[[N,N-dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanyl]amino]propyl] ester
emiltatug ledadotin [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens VTCN1(V-set domain containing T cell activation inhibitor 1, B7 family member H4, B7H4, B7-H4)], Homo sapiens monoclonal antibody, conjugated at glycosylated asparaginyl residues to a derivative of auristatin, with a ratio of 1 to 6, via a cleavable linker
