TIVIDENOFUSP ALFA
UNII QLD7UJN8CF

Substance Identification & Data

This profile provides standardized clinical and technical data for Tividenofusp Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) QLD7UJN8CF.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2641020-57-5 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

QLD7UJN8CF

CAS Registry Number

2641020-57-5

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

TIVIDENOFUSP ALFA

Official standardized name for this substance within the FDA UNII nomenclature system.

Molecular Formula

QLD7UJN8CF

The specific atomic composition represented as a molecular structure string.

NCI Thesaurus

C199121

National Cancer Institute reference terminology for clinical and research data.

INN ID

12197

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

LM-187

Identifier assigned by the United States Adopted Names Council.

Substance Type

Tividenofusp Alfa

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Tividenofusp Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

Tividenofusp Alfa

Tividenofusp Alfa-EKNM

Common Names & Synonyms

DNL-310, RECOMBINANT IDURONATE 2-SULFATASE

ENZYME TRANSPORT VEHICLE SPECIFIC FOR THE TRANSFERRIN RECEPTOR FUSED TO IDURONATE 2-SULFATASE

ETV:IDS

Iduronate-2-sulfatase (human) fusion protein with immunoglobulin Fcab, anti-(human type 1 transferrin receptor) (synthetic human γ1-chain 2), (536→6′),(539→9′)-bis(disulfide) with immunoglobulin Fcab anti-(human type 1 transferrin receptor) (synthetic human γ1-chain 1)

TIVIDENOFUSP ALFA [USAN]

human iduronate 2-sulfatase (IDS, α- L-iduronate sulfate sulfatase, EC:3.1.6.13) pro-protein (1-525), fused via the peptide linker 526 GGGGS 530 to a human immunoglobulin G1 C-terminal Fc fragment (531-757) variant (L 544>A, L 545>A, T 676>S, L 678>A, Y 717 V), disulfide bridged to an engineered human immunoglobulin G1 anti-(human type 1 transferrin receptor (TfR1)) C-terminal Fc fragment (1'-227'), variant (L 14' >A, L 15' >A, T146' >W, N 164' >Y, Q 166' >T, P 167' >E, E 168' >W, N 169' >A, D 193' >T, S 195' >E, R 196' >E, N201' >F), heterodimer, produced in Chinese hamster ovary (CHO) cells, glycoform alfa (human iduronate 2-sulfatase (IDS, α-L-iduronate sulfate sulfatase, idursulfase, EC:3.1.6.13, UniProt:P22304), pro-protein (1-525), fused via the peptidic linker G4 S (526-530) with a human immunoglobulin G1 hinge-CH2-CH3 Fc fragment [Homo sapiens IGHG1*01 (531-757) (hinge (531-540, N-terminal hinge residues EPKSC deleted), CH2L 544>A, L 545>A (541-650), CH3 T676>S, L 678>A, Y 717 >V(651-755), CHS (756-757))], (536-6':539-9')-bisdisulfide with a human immunoglobulin G1 hinge-CH2-CH3 Fc fragment [Homo sapiens IGHG1*01 (1'-227') (hinge (1-10), CH2 L 14' >A, L 15' >A (11-120), CH3 T146' >W, N 164' >Y, Q166' >T, P 167' >E, E 168' >W, N 169' >A, D193' >T, S 195' >E, R 196' >E, N 201' >F engineered for binding to the human type 1 transferrin receptor (TfR1) (121-225), CHS (226-227))], produced in Chinese hamster ovary (CHO) cells, glycoform alfa)

tividenofusp alfa [INN]