DISITAMAB VEDOTIN
UNII RB3U3A1S27

Substance Identification & Data

This profile provides standardized clinical and technical data for Disitamab Vedotin, uniquely identified by the FDA Unique Ingredient Identifier (UNII) RB3U3A1S27.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2136633-23-1 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

RB3U3A1S27

CAS Registry Number

2136633-23-1

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

DISITAMAB VEDOTIN

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C169918

National Cancer Institute reference terminology for clinical and research data.

INN ID

10933

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

MN-186

Identifier assigned by the United States Adopted Names Council.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Disitamab Vedotin. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

DISITAMAB VEDOTIN

Common Names & Synonyms

DISITAMAB VEDOTIN [INN]

DISITAMAB VEDOTIN [USAN]

DISITAMAB VEDOTIN [WHO-DD]

IMMUNOGLOBULIN G1, ANTI-(HUMAN TYROSINE KINASE RECEPTOR ERBB2) (HUMAN-MUS MUSCULUS MONOCLONAL RC48-270A4023 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL RC48-270A4023 .KAPPA.-CHAIN, DIMER, THIOETHER WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOHEXYL)-L-VALYL-N5-(AMINOCARBONYL)-L-ORNITHYL)AMINO)PHENYL)METHOXY)CARBONYL)-N-METHYL-L-VALYL-N-((1S,2R)-4-((2S)-2-((1R,2R)-3-(((1R,2S)-2-HYDROXY-1-METHYL-2-PHENYLETHYL)AMINO)-1-METHOXY-2-METHYL-3-OXOPROPYL)-1-PYRROLIDINYL)-2-METHOXY-1-((1S)-1-METHYLPROPYL)-4-OXOBUTYL)-N-METHYL-L-VALINAMIDE

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS ERBB2 (EPIDERMAL GROWTH FACTOR RECEPTOR 2, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2, EGFR2, HER2, HER-2, P185C-ERBB2, NEU, CD340)), HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO AURISTATIN E; GAMMA1 HEAVY CHAIN HUMANIZED (1-445) (VH (HOMO SAPIENS IGHV1-69-2*01 (83.5%) -(IGHD) -IGHJ1*01 (92.9%)) (8.8.8) (1-115) -HOMO SAPIENS IGHG1*03V, G1M3>G1M17, NG1M1 (CH1 R120>K (212) (116-213), HINGE (214-228), CH2 (229-338), CH3 E12 (354), M14 (357) (339-443), CHS (444-445)) (116-445)) (218-212')-DISULFIDE WITH KAPPA LIGHT CHAIN HUMANIZED (1'-212') (V-KAPPA (HOMO SAPIENS IGKV1-39*01 (83.3%) -IGKJ4*01 (100%))(6.3.7) (1'-105') -HOMO SAPIENS IGKC*01 (100%) KM3 A45.1 (151), V101 (189) (106'-212')); DIMER (224-224'':227-227'')-BISDISULFIDE; CONJUGATED ON AN AVERAGE OF 4 CYSTEINYL TO MONOMETHYLAURISTATIN E (MMAE), VIA A CLEAVABLE MALEIMIDOCAPROYL-VALYL-CITRULLINYL-PAMINOBENZYLOXYCARBONYL (MC-VAL-CIT-PABC) TYPE LINKER

Technical Codes

RC48-ADC

External Clinical & Regulatory Resources

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